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H. Oizumi



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    P1.13 - Radiology/Staging/Screening (ID 699)

    • Event: WCLC 2017
    • Type: Poster Session with Presenters Present
    • Track: Radiology/Staging/Screening
    • Presentations: 1
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      P1.13-011c - A Study on the Prognosis of Hilar and Interpulmonary Lymph Nodes Patients with Pathologic T1N1M0 and T2N1M0 Disease in NSCLC (ID 8770)

      09:30 - 09:30  |  Author(s): H. Oizumi

      • Abstract
      • Slides

      Background:
      Patients with N1 non-small cell lung carcinoma (NSCLC) represent a heterogeneous subgroups.we reviewed our previous cases of pT1N1M0 and pT2N1M0 NSCLC and the influence of the type of lymph node involvement on survival and recurrence was investigated.

      Method:
      A total of 106 consecutive patients who underwent complete tumor resection and mediastinal lymph nodes dissection for pT1N1M0 and pT2N1M0 NSCLC between 1981 and 2015 were retrospectively reviewed.

      Result:
      The overall 5-year survival of patients with T1-2N1M0 disease was 32.4%. the 5-year survival rate differed significantly according to the type of lymph node involvement. The 5-year survival rate for patients with hilar lymph node involvement, interpulmonary lymph node involvement was 50.2%, 30.1%,the survival curves of two groups had significant differences. In T1 patient, the 5-year survival rate for patients with hilar lymph node involvement, interpulmonary lymph node involvement was 46.2%, 30.1%. In T2 patient, the 5-year survival rate for patients with hilar lymph node involvement, interpulmonary lymph node involvement was 40%, 12%.

      Conclusion:
      In patients with N1 NSCLC, survival differs according to the type of lymph node involvement.patients with only inter-pulmonary lymph node involvement have a better prognosis, whereas patients with hilar lymph node involvement have a poorer prognosis. In T2 patients, hilar lymph node involvement represents poorer disease. Patients with pN1 disease represent a heterogeneous group that may be subdivided according to the level of the involved N1 station.

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