Author of

• 20191

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  P3.12 - Pulmonology/Endoscopy (ID 728)

  • Event: WCLC 2017
  • Type: Poster Session with Presenters Present
  • Track: Pulmonology/Endoscopy
  • Presentations: 1
  • Moderators:
  • Coordinates: 10/18/2017, 09:30 - 16:00, Exhibit Hall (Hall B + C)

  • 24596

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    P3.12-004b - All Cause In-Hospital Mortality on Diagnostic Bronchoscopy in Lung Cancer Patients: Data from the Japanese DPC Database (ID 10399)

    09:30 - 09:30  |  Author(s): Y. Yamauchi
    • Abstract
    • Slides

    Background:
    Due to recent technical advances in bronchoscopy and improvement of molecular targeted therapy, physicians may perform diagnostic bronchoscopy (DB) even in lung cancer patients with poor general status. As for the safety in diagnostic bronchoscopy, there have been little evidence of perioperative mortality, especially in lung cancer patients. We aimed to evaluate the short-term all cause in-hospital mortality not only for adverse events of bronchoscopy, but also for any cause in lung cancer patients who underwent DB.
    
    Method:
    We retrospectively collected data of lung cancer patients who underwent bronchoscopy and who were hospitalized between July 2010 and 31 March 2014. Bronchoscopy without taking samples for histology nor cytology, bronchoscopy under mechanical ventilation and therapeutic bronchoscopy were excluded from DB in our study. The primary outcome of this study was all-cause in-hospital mortality within 7 days after DB. We accessed factors, including patients’ ADL (Barthel index) score, comorbidities at admission, and lung cancer staging.
    
    Result:
    A total of 77,755 adult lung cancer cases in 954 hospitals underwent DB in inpatient settings. Multivariable logistic regression analysis of factors associated with all-cause mortality within 7 days after DB showed that mortality was associated with sex (adjusted odds ratio (OR); 0.58, (95% CI; 0.44–0.76)), Barthel index score (5.70, 4.48–7.25), lung cancer stage III (3.65, 1.35-9.83)or IV (4.77, 1.89-11.99), Chronic heart failure (2.76, 1.92-1.34), and Interstitial pneumonia (2.58, 1.79-1.24).
    
    Conclusion:
    All-cause in-hospital mortality of lung cancer patients after DB were significantly associated with ADL score, lung cancer stage and comorbidities.
    
    

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