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H.K. Kim
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P3.16 - Surgery (ID 732)
- Event: WCLC 2017
- Type: Poster Session with Presenters Present
- Track: Surgery
- Presentations: 1
- Moderators:
- Coordinates: 10/18/2017, 09:30 - 16:00, Exhibit Hall (Hall B + C)
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P3.16-020 - Long Term Changes of Pulmonary Function After Lobectomy (ID 10079)
09:30 - 09:30 | Author(s): H.K. Kim
- Abstract
Background:
Postoperative pulmonary function changes after lung resection and that decline is determined by the extent of lung resection. It has been known that pulmonary function after surgery recovers gradually within 3 months to 1 year and finally reaches a steady state. However, the long-term respiratory function is unknown. We investigated the changes in respiratory function after thoracic surgery in patients who performed more than segmentectomy to evaluate the long-term effect of lung resection.
Method:
A total of 99 patients who underwent lobectomy followed up serial pulmonary function at postoperative 1month, 6months, 1,2,3 and 5 years. We investigated the serial changes of forced expiratory volume per 1 seconds (FEV~1~%), diffusion capacity of carbon monoxide (DL~CO~%) by groups of minimal invasive surgery and adjuvant chemotherapy.
Result:
The reduced postoperative FEV~1~% recovered to preoperative value until postoperative 6 to 1 year and declined yearly. The value of DL~CO~% increased to preoperative value until postoperative 2 years and remained steady state. There was no significant change in at more than 2 years follow-up (Fig.1). The value of DL~CO~% was decreased significantly during adjuvant therapy (p=0.031) (Fig.2) and the patients performed VATS lobectomy showed faster recovery in FEV~1~% and DL~CO~% compared to thoracotomy group (p=0.001) (Fig.3 and 4). Figure 1
Conclusion:
The respiratory function after lung lobectomy recovered gradually over postoperative 2 years. Adjuvant chemotherapy or thoracotomy showed negative impact on the postoperative pulmonary function.