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O. Ghdes



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    P3.13 - Radiology/Staging/Screening (ID 729)

    • Event: WCLC 2017
    • Type: Poster Session with Presenters Present
    • Track: Radiology/Staging/Screening
    • Presentations: 1
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      P3.13-026 - Non-Small Cell Lung Cancer: Imaging of Recurrences After Surgery (ID 9983)

      09:30 - 09:30  |  Author(s): O. Ghdes

      • Abstract

      Background:
      Lung cancer has a poor prognosis unless patients are operated. However, few patients may undergo surgery. Recurrences are not rare and they increase the mortality. The objective of this study is to appreciate the frequency of recurrences after surgery in non-small lung cancer (NSCLC) in our institution and to correlate them to TNM classification and histological subtypes.

      Method:
      Retrospective review of 127 patients (106 men and 21 women) aged between 19 and 80 years with NSCLC that were operated. All patients had chest, abdomen and brain computed tomography (CT) in their follow up. We precised for each patient the histological type of the lung cancer, the c and p TNM stages, the resection type and the other treatments prescribed, the recurrence site and the delay between the surgery and the recurrence.

      Result:
      Recurrences were observed in 35 patients (27.5%). They had either a lobectomy (n=30), a pneumonectomy (n=4) or a wedge (n=1). Recurrences were located to the chest in 36 cases (half of them occurred in the operated lung) and in extra-thoracic organs in 13 cases; the brain was the mostly involved. The delay between surgery and recurrence ranged between 1 month and 7 years. Fourteen patients had a recurrence within the first year after surgical removal of their tumor. Recurrences were mostly observed in patients with T4 stage (23%), N3 stage (66.6%), stage III cancer (49%), and with adenocarcinoma. An under-estimation of the cT and cN stages was observed in 5.6% and 27.5% of patients, respectively.

      Conclusion:
      Recurrences in patients with surgically removed lung cancer are not rare. They depend on its histological type and on the cT and cN stages.