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M. Affes
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P3.13 - Radiology/Staging/Screening (ID 729)
- Event: WCLC 2017
- Type: Poster Session with Presenters Present
- Track: Radiology/Staging/Screening
- Presentations: 2
- Moderators:
- Coordinates: 10/18/2017, 09:30 - 16:00, Exhibit Hall (Hall B + C)
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P3.13-025 - Spinal Cord and Cauda Equina Compression in Lung Cancer (ID 9946)
09:30 - 09:30 | Author(s): M. Affes
- Abstract
Background:
Spinal cord compression is one of the most disabling complications in lung cancer. It may be caused either by the tumor itself or by metastatic involvement of the spine and meninges. The goal of this work is to appreciate characteristic of spinal cord compression in lung cancer.
Method:
Retrospective review of the MRI data of patients with lung cancer presenting with neurological symptoms caused by medullary or cauda equine compression. Only patients with abnormal findings were retained. All exams were performed by a 1.5 T machine.
Result:
From January 2014 to December 2016, only 24 patients (23 males and 1 female) were referred to the imaging department of our institution for medullary compression exploration. Their average age was 57 years. Seventeen patients had adenocarcinoma. Three patients were classed stage IIIB and 18 were classed stage IV. Medullary compression was caused by direct compression (12 cases) of the tumor or by a spine metastases (12 cases). One spine region was involved in 18 patients with dorsal location in 13 patients. In three cases, the compression concerned the cauda equina. Myelopathy was noted in 15 of the 21 patients with spinal cord compression.
Conclusion:
Spinal compression is not frequent in lung cancer. It is mainly observed in advanced stages. It may occur by direct tumor invasion or by vertebral metastatic extension.
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P3.13-026 - Non-Small Cell Lung Cancer: Imaging of Recurrences After Surgery (ID 9983)
09:30 - 09:30 | Author(s): M. Affes
- Abstract
Background:
Lung cancer has a poor prognosis unless patients are operated. However, few patients may undergo surgery. Recurrences are not rare and they increase the mortality. The objective of this study is to appreciate the frequency of recurrences after surgery in non-small lung cancer (NSCLC) in our institution and to correlate them to TNM classification and histological subtypes.
Method:
Retrospective review of 127 patients (106 men and 21 women) aged between 19 and 80 years with NSCLC that were operated. All patients had chest, abdomen and brain computed tomography (CT) in their follow up. We precised for each patient the histological type of the lung cancer, the c and p TNM stages, the resection type and the other treatments prescribed, the recurrence site and the delay between the surgery and the recurrence.
Result:
Recurrences were observed in 35 patients (27.5%). They had either a lobectomy (n=30), a pneumonectomy (n=4) or a wedge (n=1). Recurrences were located to the chest in 36 cases (half of them occurred in the operated lung) and in extra-thoracic organs in 13 cases; the brain was the mostly involved. The delay between surgery and recurrence ranged between 1 month and 7 years. Fourteen patients had a recurrence within the first year after surgical removal of their tumor. Recurrences were mostly observed in patients with T4 stage (23%), N3 stage (66.6%), stage III cancer (49%), and with adenocarcinoma. An under-estimation of the cT and cN stages was observed in 5.6% and 27.5% of patients, respectively.
Conclusion:
Recurrences in patients with surgically removed lung cancer are not rare. They depend on its histological type and on the cT and cN stages.