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Y. Kunihiro
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P3.13 - Radiology/Staging/Screening (ID 729)
- Event: WCLC 2017
- Type: Poster Session with Presenters Present
- Track: Radiology/Staging/Screening
- Presentations: 1
- Moderators:
- Coordinates: 10/18/2017, 09:30 - 16:00, Exhibit Hall (Hall B + C)
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P3.13-013 - Association of Pleural Tags with Visceral Pleural Invasion of Peripheral Lung Cancer (ID 8716)
09:30 - 09:30 | Author(s): Y. Kunihiro
- Abstract
Background:
Visceral pleural invasion (VPI) is an important prognostic factor for patients with peripheral lung cancer, but its accurate preoperative evaluation with CT is difficult. Pleural tags, which are defined as one or more linear strands that extend from the tumor surface to the pleura, are sometimes seen in peripheral lung cancer that does not abut the pleura. However, studies evaluating the correlation of pleural tags with VPI are limited. The aim of this study was to evaluate the association of pleural tags with VPI of peripheral lung cancer, especially focusing on the type of pleural tags.
Method:
A total of 183 patients were retrospectively analyzed. They underwent pulmonary resection in our hospital between January 2009 and December 2015 for peripheral lung cancer ≦2 cm in solid tumor diameter and dose not abut the pleura. Forms of pleural tag were classified as follows; linear tag, linear tag with soft tissue component at the pleural end, and soft tissue cord-like tag. The relationships between VPI and clinical factors including the forms of pleural tag were analyzed using chi-square for independence tests, and then multivariate logistic regression models were applied.
Result:
Histologically, 23 (12.6%) patients were proven to have VPI. Overlap and multiple forms of pleural tags were frequently seen. Multivariate analysis revealed that tumors with linear tag with soft tissue component at the pleural end had significant association with VPI (p = 0.008). Sensitivity and specificity were 47.8% and 83.8%, respectively, in the prediction of VPI with this type of pleural tag. Presence of multiple linear tags also was associated with VPI (p = 0.036).
Conclusion:
Specific forms of pleural tag can predict VPI of peripheral lung cancer ≦2 cm in solid tumor diameter and dose not abut the pleura.