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K. Purbhoo
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P3.13 - Radiology/Staging/Screening (ID 729)
- Event: WCLC 2017
- Type: Poster Session with Presenters Present
- Track: Radiology/Staging/Screening
- Presentations: 1
- Moderators:
- Coordinates: 10/18/2017, 09:30 - 16:00, Exhibit Hall (Hall B + C)
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P3.13-005 - Characteristics of Primary Lung Cancer on PET/CT Imaging in the South African Population (ID 8109)
09:30 - 09:30 | Author(s): K. Purbhoo
- Abstract
Background:
The incidence of primary lung cancer in developing countries has increased and it constitutes the most common cause of cancer related mortality. Some radiological features can be predictive for different histologies and have prognostic utility. One of the features of imaging in the Fleischner Society guideline is common occurrence in the upper lobe with predilection for the right lung.
Method:
A retrospective audit was done to compare the characteristics of primary lung cancer in patients in our environment. Images and patient reports were obtained from our local database archives or from the hospital records. The location of the primary was defined as peripheral if located in the outer third of the lung parenchyma on axial CT or PET/CT images, and defined as central if located anywhere else. Lobe location was also recorded for each primary.
Result:
We reviewed 42 patients with histologically confirmed lung cancer that were referred for PET/CT imaging. The age range was 37- 80 years. Sixty nine percent (n=29) were males 31% (n=14) were females. The most common histologic subtype was adenocarcinoma (48%), followed by squamous cell lung cancer (40%), and small cell lung cancer (12%). Most of the primary pathology were in the right lung (60%, n= 25) as compared to the left lung (40%, n=17). The upper lobes were more commonly affected (64%, n=27), followed by the lower lobes (33%, n=14), and right middle lobe (3%, n=1). Sixty percent (n=25) of tumors were centrally located, of which 64% were of the histologic subtype squamous cell ca. Our findings also showed that 26% (n=11) of patients had metastases to ipsilateral lobes, and 24% (n=10) had metastases to the opposite lung. There were 22% (n=22) of patients that had only nodal metastases and 12% (n=5) had both nodal and visceral metastases. Nineteen percent of patients (n=8) had no evidence of nodal or visceral metastases.
Conclusion:
Our findings conform to those found in literature that primary lung cancer involves the right lung more often and involves the upper lobes more commonly. It also showed that squamous cell lung cancers are mostly central and most adenocarcinomas are peripheral in location.
