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P. Kumbhaj



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    P2.10 - Nursing/Palliative Care/Ethics (ID 711)

    • Event: WCLC 2017
    • Type: Poster Session with Presenters Present
    • Track: Nursing/Palliative Care/Ethics
    • Presentations: 1
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      P2.10-007 - Quality of Life across Various Treatment Lines in Metastatic Lung Cancer Patients (ID 7442)

      09:30 - 09:30  |  Author(s): P. Kumbhaj

      • Abstract
      • Slides

      Background:
      Lung cancer is second most common cancer in Indian men and is a leading cause of cancer deaths in India. Most lung cancer patients in India are diagnosed at an advanced or metastatic stage and predominantly receive palliative treatment. In patients with metastatic lung cancer quality of life (QOL) improvement is the main treatment goal since survival can be prolonged only marginally despite the use of several new therapeutic modalities.

      Method:
      We divided metastatic lung cancer patients into four groups depending on the treatment they received: Group A - palliative chemotherapy, Group B – palliative radiotherapy, Group C – both palliative chemotherapy and radiotherapy and Group D – only symptomatic therapy and best supportive care. All patients completed quality of life questionnaire for lung cancer (EORTC QLQ C30 version 3.0 and LC13) translated in the native language before treatment and on follow up after receiving the planned treatment. Apart from QOL questionnaires few other variables were also studied including age, gender, histology, smoking status, stage, performance status and financial status.

      Result:
      92 patients were prospectively included in the study with 23 patients in each group. All aspects of functioning were most preserved in patients who received palliative chemotherapy (physical, emotional, social, cognitive, role and global QOL) and were most disturbed in patients who received only symptomatic therapy. Chemotherapy reduced symptoms like dyspnea, insomnia, loss of appetite, dysphagia, and haemoptysis, but also increased nausea, vomiting, fatigue and alopecia. Radiotherapy reduced pain, coughing, dyspnea, dysphagia and hemoptysis but worsened physical and social functioning.

      Conclusion:
      Any modality of treatment is superior to the use of only symptomatic treatment in improving QOL in metastatic lung cancer patients and therefore some form of treatment should be offered if possible. Patients on chemotherapy have better QOL than those on radiotherapy or combined chemotherapy and radiotherapy.

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