Virtual Library
Start Your Search
A. Kuroda
Author of
-
+
P2.09 - Mesothelioma (ID 710)
- Event: WCLC 2017
- Type: Poster Session with Presenters Present
- Track: Mesothelioma
- Presentations: 1
- Moderators:
- Coordinates: 10/17/2017, 09:30 - 16:00, Exhibit Hall (Hall B + C)
-
+
P2.09-007 - Pleural Biopsy in Patients Suspected of Malignant Pleural Mesothelioma Consecutive 377 Cases (ID 9022)
09:30 - 09:30 | Author(s): A. Kuroda
- Abstract
Background:
Video-assisted thoracic surgery (VATS) pleural biopsy is a most reliable diagnostic procedure for malignant pleural mesothelioma (MPM), however, its surgical outcomes are still unknown. The purpose of this study was to analyze the surgical outcome of VATS pleural biopsy in patients suspected of MPM.
Method:
A total of 377 patients received VATS pleural biopsy with suspected of MPM from March 2004 to December 2016 were included in the study. We evaluated their surgical outcome based on diagnostic accuracy, mortality, morbidity.
Result:
Of 377 patients, VATS pleural biopsy led to diagnosis as MPM in 250, carcinomatous pleurisy in 22 and chronic pleuritis in 105. However, of these 105 chronic pleuritis patients, 10 patients were received re-biopsy to establish the definitive diagnosis. Re-biopsy revealed 9 patients finally diagnosed as MPM, and 1 patient as carcinomatous pleurisy. The diagnostic accuracy of initial VATS pleural biopsy for MPM was 96.5% (250/259). The causes of miss-diagnosis were sampling error in all 9 cases, and the causes of sampling error as follows: no visible tumor in 4, complicated empyema in 2, severe adhesion in 2, and desmoplastic MPM in 1. The median postoperative stay was 5 days (1-114).Postoperative complication. Median age was 68 years (range, 40-85 years), with a 5- day (range 1-114 days) median length of stay. Postoperative complication occurred in 25 patients (5.7%), and 1 patient (0.26%) died due to postoperative empyema. Complications of this study included the following: injury of lung parenchyma in 7, wound infection in 4, re-expanding pulmonary edema in 3, empyema, gastrointestinal perforation and delirium in 2, fetal arrhythmia, cholecystitis hemothorax, liver dysfunction, acute respiratory failure in 1.
Conclusion:
VATS pleural biopsy could lead to definitive diagnosis in most case of MPM, but we should consider their limitation of diagnostic ability and the risk of VATS biopsy.
