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K. Shimazu



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    P2.06 - Epidemiology/Primary Prevention/Tobacco Control and Cessation (ID 707)

    • Event: WCLC 2017
    • Type: Poster Session with Presenters Present
    • Track: Epidemiology/Primary Prevention/Tobacco Control and Cessation
    • Presentations: 1
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      P2.06-003 - Retrospective Study of Cerebral Thromboembolism Occurring before and after Detection of Lung Cancer (Trousseau Syndrome) (ID 8021)

      09:30 - 09:30  |  Author(s): K. Shimazu

      • Abstract
      • Slides

      Background:
      Armand Trousseau reported the concept of blood coagulation disorders accompanying malignancies in 1865. Currently, Trousseau syndrome is also defined as cerebral infarction due to malignant tumors. Among cerebral infarction patients with cancer, lung cancer (LC) and prostatic cancer are reported to be relatively likely to develop Trousseau syndrome. When it occurs, treatment for cancer is difficult, and prognosis is poor. We conducted a retrospective study of LC patients before and after the onset of cerebral infarction, respectively.

      Method:
      Among 1,185 cases of patients with LC from 2006 to 2016, we registered 15 cases with complications of cerebral infarction before or after LC detected. Fifteen patients were divided into two groups. One was a group of cerebral infarction before the detection of LC (A group) and the other was a group of infarction complication after LC detection (B group).

      Result:
      Patient characteristics of A group consisting of 8 cases and B group consisting of 7 cases were as follows, respectively: male/female, 5/3 and 3/4 cases; median age, 67.4 and 72.0 years; small cell lung cancer/squamous cell carcinoma/adenocarcinoma/large cell neuroendocrine carcinoma, 2/1/4/1 and 1/1/4/1 cases; stage I/II/III/IV, 2/1/1/4 and 0/0/2/5 cases; treatment intervention for LC, 8 and 3 cases. Median survival time was respectively 13.7 months for A group and 5.5 months for B group, although there was not significant in Kaplan-Meier survival curve.

      Conclusion:
      Lung cancer detected after or at the same time of cerebral infarction is considered to have better prognosis since early diagnosis and treatment against LC is possible.

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