Author of

• 18973

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  P2.01 - Advanced NSCLC (ID 618)

  • Event: WCLC 2017
  • Type: Poster Session with Presenters Present
  • Track: Advanced NSCLC
  • Presentations: 1
  • Moderators:
  • Coordinates: 10/17/2017, 09:00 - 16:00, Exhibit Hall (Hall B + C)

  • 23147

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    P2.01-024 - Prognostic Value of Body Fat Mass Ratio in Lung Cancer Patients (ID 8746)

    09:00 - 09:00  |  Author(s): M.A. Kaplan
    • Abstract

    Background:
    Lung cancer is one of the most leading cause of death. One of the prognostic factors that affect survival in lung cancer is weight loss. İn this study, we aimed to investigate the effect of body fat mass ratio on prognosis and survival in advanced stage small cell lung cancer (SCLC) and non-small cell lung cancer (NSCLC) patients.
    
    Method:
    Between September 2014 and July 2015, 200 patients who were diagnosed with advanced lung cancer and whose body fat mass percentage and Body Mass Index (BMI) were determined by using Tanita Body Composition Analyzer during the admission in our institution were included in the study. All patients were analyzed for survival in terms of body fat mass ratio and BMI and other parameters.
    
    Result:
    One hundred and sixty four of the patients (82%) were male. The median age was 56.5 (28-93) years. Forty seven (23.5%) of the patients were diagnosed with SCLC and 153 (76.5%) were diagnosed with NSCLC. In univariate analysis; There was no statistically significant on survival effect of, gender, age (<65,> 65), histological diagnosis (SCLC, NSCLC), smoking history, performance status, weight loss during the last 6 months and BMI (>30, <30) (p> 0.05). In the univariate analysis the survival was effected by comorbid disease presence [median 11.4 months in patients with comorbid disease and 19.2 months in patients without comorbid disease (p = 0.012)], and body fat mass ratio [median 16.4 months in <30% and 29.2 months in >30% (p = 0.038)], and they were found statistically significant. In multivariate analysis; There was no statistically significant on survival effect of gender, age (<65 ,> 65), histological diagnosis (SCLC and NSCLC), BMI (<25 and> 25), performance status, however comorbid disease (p = 0.01) and body fat mass ratio (p = 0.033) were found to have a significant effect on survival.
    
    Conclusion:
    In patients with advanced lung cancer, body fat mass ratio were found to be independent prognostic factor for over all survival.