Virtual Library
Start Your Search
M. Yao
Author of
-
+
P1.17 - Thymic Malignancies/Esophageal Cancer/Other Thoracic Malignancies (ID 703)
- Event: WCLC 2017
- Type: Poster Session with Presenters Present
- Track: Thymic Malignancies/Esophageal Cancer/Other Thoracic Malignancies
- Presentations: 1
- Moderators:
- Coordinates: 10/16/2017, 09:30 - 16:00, Exhibit Hall (Hall B + C)
-
+
P1.17-018 - Distribution of Ectopic Thymus in Chinese Patients: A Preliminary Study (ID 8630)
09:30 - 09:30 | Author(s): M. Yao
- Abstract
Background:
Thymectomy has been a mainstay in the treatment of myasthenia gravis. However, the situation of ectopic thymic tissues remains unknown .The aim of this study was to investigate the distribution of ectopic thymic tissue in Chinese patients using flow cytometry (FCM).
Method:
The resected tissues from 54 patients with MG was divided and classified into: right pericardiacophrenic angle (Number 1), left pericardiacophrenic angle (2), peritracheal (3), right phrenic nerve (4), left phrenic nerve (5), superficial cervical (6) and deep cervical (7). Cells were then stained with anti-CD4, anti-CD8, anti-CD3, anti-TCRvβ, anti-CD56, anti-CD20, anti-CD14,anti-CD11b and labelled with live/dead for analyzing by BD LSRFortessa.
Result:
Ectopic thymic tissue incidence in individual locations was as follows: 47.8% (22 in 46)right pericardiacophrenic angle, 39.5% (15 in 38) left pericardiacophrenic angle, 57.6% (19 out of 33) peritracheal, 83.3% (5 in 6) right phrenic nerve, 57.1% (4 out of 7) left phrenic nerve, 100% (4 specimens) superficial adipose and 100% (8 specimens) deep neck adipose (Fig 2). Figure 1Figure 2
Conclusion:
Our study indicated that the incidence of ectopic thymic tissues was more frequently than former acknowledge by HE staining test.
