Author of

• 20161

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  P1.12 - Pulmonology/Endoscopy (ID 698)

  • Event: WCLC 2017
  • Type: Poster Session with Presenters Present
  • Track: Pulmonology/Endoscopy
  • Presentations: 1
  • Moderators:
  • Coordinates: 10/16/2017, 09:30 - 16:00, Exhibit Hall (Hall B + C)

  • 22748

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    P1.12-001 - Flexible Bronchoscopic Cryotherapy in Patients with Malignant Central Airway Obstruction (ID 8428)

    09:30 - 09:30  |  Author(s): Y.M. Ko
    • Abstract

    Background:
    Although malignant central airway obstruction has poor prognosis, cryotherapy can be used as a palliative treatment. The objective of this study is to evaluate the role of flexible bronchoscopic cryotherapy in patients with malignant central airway obstruction.
    
    Method:
    Clinical data of patients who performed flexible bronchoscopic cryotherapy for recanalization of malignant central airway obstruction from March 2014 to September 2016 were analyzed retrospectively.
    
    Result:
    29 patients (21 males) were enrolled. Median age was of 65 years (range, 54-82) and median ECOG performance status was 3 (range, 1-3). Causes of malignant central airway obstruction were primary lung cancer of 21 cases (Squamous cell carcinoma, 12 cases; small cell carcinoma, 9 cases) and endobronchial metastasis of 8 cases (soft tissue sarcoma, 2 cases; renal cell cancer, 4 cases; glottis cancer, 1 case; endometrial cancer, 1 case). Obstruction sites were as follows: carina and both main bronchus, 4 cases; left main bronchus, 9 cases; right main bronchus, 8 cases; bronchus intermedius, 8 cases. Degree of obstruction was classified into three categories: complete, 6 cases; partial non-passable with scope, 5 cases; partial passable with scope, 18 cases. Type of obstruction was classified into two types: intrinsic obstruction, 8 cases (all endobronchial metastasis); extrinsic obstruction, 21 cases (all primary lung cancer). Complete recanalization was achieved in 8 cases (27.6%), and all of them were endobronchial metastasis. Partial recanalization was achieved 21 cases (72.4%). Dyspnea was improved in 23 patients (79.3%). There was no immediate complication, such as respiratory failure or massive bleeding. Figure 1
    
    
    
    Conclusion:
    Cryotherapy with flexible bronchoscopy is a feasible and effective treatment for malignant central airway obstruction, especially due to endobronchial metastasis. For more clarification, further prospective study of large scale will be required.