Author of

• 20155

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  P1.06 - Epidemiology/Primary Prevention/Tobacco Control and Cessation (ID 692)

  • Event: WCLC 2017
  • Type: Poster Session with Presenters Present
  • Track: Epidemiology/Primary Prevention/Tobacco Control and Cessation
  • Presentations: 1
  • Moderators:
  • Coordinates: 10/16/2017, 09:30 - 16:00, Exhibit Hall (Hall B + C)

  • 22659

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    P1.06-015 - Analysis of Relationship Between Non-Small Cell Lung Cancer and Nicotine Dependence (ID 9700)

    09:30 - 09:30  |  Author(s): S. Paik
    • Abstract

    Background:
    Approximately 80% of non-small cell lung cancers (NSCLC) are related to smoking, and smokers are 10-20 times more likely to have NSCLC than non-smokers. Nicotine has a 1.5 times higher rate of post-exposure dependence than other drugs, making it very difficult to stop. Thus, the aim of this study is to clarify the association between NSCLC and nicotine dependence.Approximately 80% of non-small cell lung cancers (NSCLC) are related to smoking, and smokers are 10-20 times more likely to have NSCLC than non-smokers. Nicotine has a 1.5 times higher rate of post-exposure dependence than other drugs, making it very difficult to stop. Thus, the aim of this study is to clarify the association between NSCLC and nicotine dependence.
    
    Method:
    We investigated the prevalence of nicotine dependence in NSCLC patients and analyzed the clinical characteristics of nicotine dependent NSCLC patients. Smoking information was assessed via questionnaires and personal interview in a cohort of 120 patients from four hospitals of the Catholic Medical Center between 2016 and 2017. Tobacco Use Disorder criteria of DSM-V, DSM-IV nicotine dependence criteria, and Fagerstrom Test for Nicotine Dependence (FNTD) were used to define nicotine dependence. Urine cotinine test was also performed to validate tobacco use.
    
    Result:
    Most of them were male (93.3%) and the average smoking amount was 40 pack years. At the time of diagnosis of NSCLC, 71.7% were current smoking status. The prevalence of nicotine dependence was 77-92% according to the diagnostic tool, DSM-V (92%), DSM-IV (78%) and FNTD (77%), which is expected to be higher in the NSCLC group compared to the general smoking population. Based on FTND scores, patients were divided into mild, moderate, and severe groups. Smoking amount was significantly higher in severe group than the others. In addition, although drinking habit scores were higher in the severe nicotine dependent group, there were no significant differences among the groups in the other parameters, such as number of attempts to quit smoking, smoking cessation success, urine cotinine test results, depression, anxiety, and quality of life.
    
    Conclusion:
    These preliminary results of the prevalence of nicotine dependence in NSCLC patients may provide medical evidence for development of intensive smoking-cessation program in NSCLC patients.