Virtual Library
Start Your Search
M.M. Hassan
Author of
-
+
P1.06 - Epidemiology/Primary Prevention/Tobacco Control and Cessation (ID 692)
- Event: WCLC 2017
- Type: Poster Session with Presenters Present
- Track: Epidemiology/Primary Prevention/Tobacco Control and Cessation
- Presentations: 1
- Moderators:
- Coordinates: 10/16/2017, 09:30 - 16:00, Exhibit Hall (Hall B + C)
-
+
P1.06-011 - Hyponatremia - Evaluation of Prevalence in Hospitalized Lung Cancer Patients and Its Prognostic Significance (ID 9528)
09:30 - 09:30 | Author(s): M.M. Hassan
- Abstract
Background:
Hyponatremia is an underestimated hazardous complication; which goes side by side since diagnosis till terminal outcome of carcinoma lung patients. The aim of study is to evaluate the prevalence of hyponatremia in hospitalized lung cancer patients and influence of hyponatremia on prognosis in same group of patients.
Method:
Observational study was conducted between July, 2015 to November, 2016 in United Hospital Cancer Care Centre. A total 200 hospitalized patients were analyzed with diagnosed carcinoma lung. These subjects were free from gross liver diseases; kidney diseases and brain metastasis. Prevalence of hyponatremia including severity (mild, moderate and severe) was evaluated. The role of hyponatremia with lung cancer was also evaluated in hospital mortality. Hyponatremia was treated with oral salt, NaCl tablets along with fluid restriction to 500 mL per day. In some cases hypertonic saline was also used. In the present study we were not assessing the prevalence of SIADH but only hyponatraemia.
Result:
Among 200 patients; NSCLC were 79.5 %( n=159) and SCLC were 20.5% (n=41). Various degree of hyponatremia was found in 63.52 % ( n=101) NSCLC patients and 56.09 %( n=23) SCLC patients. There was no statistical significance in prevalence of hyponatremia between histological types of lung cancer. Out of 200 patients, 124 patients had mild, moderate and sever hyponatremia which was 61.29 %( n=76), 27.42 %( n=34) and 11.29 %( n=14) respectively. Among 124 hyponatremic patients 23.38% (n=29) died and 76.61 %( n=95) survived. And remaining 76 normo-natremic patients 10.53% (n=8) died of their illness and 89.47 %( n=68) survived. In patients with lung cancer with hyponatremia compared to patient with lung cancer without hyponatremia; a significant increase in hospital mortality was found. (23.38% Vs 10.53%) (p <0.001)
Conclusion:
Hyponatremia is common abnormality found in approximately 62% of lung cancer patients. It is also considered as a significant prognostic factor associated with mortality of lung cancer patient. In future large prospective multicenter study is needed to better understand the relation of hyponatremia in lung cancer patient for both management and outcome.
