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C.H. Kim
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P1.05 - Early Stage NSCLC (ID 691)
- Event: WCLC 2017
- Type: Poster Session with Presenters Present
- Track: Early Stage NSCLC
- Presentations: 1
- Moderators:
- Coordinates: 10/16/2017, 09:30 - 16:00, Exhibit Hall (Hall B + C)
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P1.05-020 - Clues of Stromal Invasion of Pulmonary Adenocarcinoma on CT, Focusing on Cicatricial Change (ID 8513)
09:30 - 09:30 | Author(s): C.H. Kim
- Abstract
Background:
To investigate whether a cicatricial change of adenocarcinoma appearing as pure ground glass opacity nodule (GGN) on CT correlate with stromal invasion.
Method:
From June 2013 to December 2016, 425 adenocarcinomas were pathologically confirmed in our institution. With a retrospective investigation of CT images and pathologic reports, we found 37 surgically resected pure GGNs. Then, we analyzed the statistical difference of the presence of cicatricial changes (traction bronchiectasis and cystic airspace dilatation) on CT between two groups according to the presence of stromal invasion (Adenocarcinoma in situ vs Invasive pulmonary adenocarcinoma).
Result:
Among the 37 pure GGNs, there were 17 adenocarcinoma in situ and 20 invasive pulmonary adenocarcinomas (13 minimally invasive adenocarcinomas and 7 adenocarcinomas). The frequencies of traction bronchiectasis (12 % vs 70 %, p<0.001) and cystic airspace dilatation (24% vs 55%, p=0.052) were higher in invasive pulmonary adenocarcinoma with or without statistical significance. The presence of either traction bronchiectasis or cystic airspace dilatation (35% vs 80%, p=0.006) was also more frequently found in the invasive pulmonary adenocarcinoma. Figure 1
Conclusion:
Cicatricial changes in adenocarcinoma presenting pure GGN may be a finding suggesting stromal invasion.
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P1.12 - Pulmonology/Endoscopy (ID 698)
- Event: WCLC 2017
- Type: Poster Session with Presenters Present
- Track: Pulmonology/Endoscopy
- Presentations: 1
- Moderators:
- Coordinates: 10/16/2017, 09:30 - 16:00, Exhibit Hall (Hall B + C)
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P1.12-001 - Flexible Bronchoscopic Cryotherapy in Patients with Malignant Central Airway Obstruction (ID 8428)
09:30 - 09:30 | Author(s): C.H. Kim
- Abstract
Background:
Although malignant central airway obstruction has poor prognosis, cryotherapy can be used as a palliative treatment. The objective of this study is to evaluate the role of flexible bronchoscopic cryotherapy in patients with malignant central airway obstruction.
Method:
Clinical data of patients who performed flexible bronchoscopic cryotherapy for recanalization of malignant central airway obstruction from March 2014 to September 2016 were analyzed retrospectively.
Result:
29 patients (21 males) were enrolled. Median age was of 65 years (range, 54-82) and median ECOG performance status was 3 (range, 1-3). Causes of malignant central airway obstruction were primary lung cancer of 21 cases (Squamous cell carcinoma, 12 cases; small cell carcinoma, 9 cases) and endobronchial metastasis of 8 cases (soft tissue sarcoma, 2 cases; renal cell cancer, 4 cases; glottis cancer, 1 case; endometrial cancer, 1 case). Obstruction sites were as follows: carina and both main bronchus, 4 cases; left main bronchus, 9 cases; right main bronchus, 8 cases; bronchus intermedius, 8 cases. Degree of obstruction was classified into three categories: complete, 6 cases; partial non-passable with scope, 5 cases; partial passable with scope, 18 cases. Type of obstruction was classified into two types: intrinsic obstruction, 8 cases (all endobronchial metastasis); extrinsic obstruction, 21 cases (all primary lung cancer). Complete recanalization was achieved in 8 cases (27.6%), and all of them were endobronchial metastasis. Partial recanalization was achieved 21 cases (72.4%). Dyspnea was improved in 23 patients (79.3%). There was no immediate complication, such as respiratory failure or massive bleeding. Figure 1
Conclusion:
Cryotherapy with flexible bronchoscopy is a feasible and effective treatment for malignant central airway obstruction, especially due to endobronchial metastasis. For more clarification, further prospective study of large scale will be required.
