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J.Y. You
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P1.05 - Early Stage NSCLC (ID 691)
- Event: WCLC 2017
- Type: Poster Session with Presenters Present
- Track: Early Stage NSCLC
- Presentations: 1
- Moderators:
- Coordinates: 10/16/2017, 09:30 - 16:00, Exhibit Hall (Hall B + C)
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P1.05-020 - Clues of Stromal Invasion of Pulmonary Adenocarcinoma on CT, Focusing on Cicatricial Change (ID 8513)
09:30 - 09:30 | Author(s): J.Y. You
- Abstract
Background:
To investigate whether a cicatricial change of adenocarcinoma appearing as pure ground glass opacity nodule (GGN) on CT correlate with stromal invasion.
Method:
From June 2013 to December 2016, 425 adenocarcinomas were pathologically confirmed in our institution. With a retrospective investigation of CT images and pathologic reports, we found 37 surgically resected pure GGNs. Then, we analyzed the statistical difference of the presence of cicatricial changes (traction bronchiectasis and cystic airspace dilatation) on CT between two groups according to the presence of stromal invasion (Adenocarcinoma in situ vs Invasive pulmonary adenocarcinoma).
Result:
Among the 37 pure GGNs, there were 17 adenocarcinoma in situ and 20 invasive pulmonary adenocarcinomas (13 minimally invasive adenocarcinomas and 7 adenocarcinomas). The frequencies of traction bronchiectasis (12 % vs 70 %, p<0.001) and cystic airspace dilatation (24% vs 55%, p=0.052) were higher in invasive pulmonary adenocarcinoma with or without statistical significance. The presence of either traction bronchiectasis or cystic airspace dilatation (35% vs 80%, p=0.006) was also more frequently found in the invasive pulmonary adenocarcinoma. Figure 1
Conclusion:
Cicatricial changes in adenocarcinoma presenting pure GGN may be a finding suggesting stromal invasion.
