Author of

• 20154

  +

  P1.05 - Early Stage NSCLC (ID 691)

  • Event: WCLC 2017
  • Type: Poster Session with Presenters Present
  • Track: Early Stage NSCLC
  • Presentations: 1
  • Moderators:
  • Coordinates: 10/16/2017, 09:30 - 16:00, Exhibit Hall (Hall B + C)

  • 22639

    +

    P1.05-017 - Prognostic Significance of Preoperative Plasma D-Dimer Level in Patients with Surgically Resected Clinical Stage I Non-Small Cell Lung Cancer (ID 8091)

    09:30 - 09:30  |  Author(s): A. Kazama
    • Abstract
    • Slides

    Background:
    The plasma D-dimer (D-dimer) level, a marker of hypercoagulation, has been reported to be associated with survival in several types of cancers. The aim of this study was to evaluate the prognostic significance of the preoperative D-dimer level in patients with surgically resected clinical stage I non-small cell lung cancer (NSCLC).
    
    Method:
    A total of 237 surgically resected NSCLC patients were included in this study. In addition to age, sex, the smoking status, etc., the association between the preoperative D-dimer level and survival was explored.
    
    Result:
    The patients were divided into two groups according to the D-dimer level: group A (≤ 1.0 µg/ml, n = 170) and group B (> 1.0 µg/ml, n = 67). The 5-year overall survival rate was 89.0 % (95 % confidence interval [CI] 77.7–95.3) for group A, 78.2 % (95 % CI 62.3–83.6) for group B (p = 0.015). A multivariate survival analysis showed that the D-dimer level was an independent significant prognostic factor, in addition to age and SUVmax of the tumor.
    
    Conclusion:
    The preoperative D-dimer level is an independent prognostic factor in patients with surgically resected clinical stage I NSCLC.
    
    

    Only Active Members that have purchased this event or have registered via an access code will be able to view this content. To view this presentation, please login or select "Add to Cart" and proceed to checkout.