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Yoshiki Negi
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P2.09 - Mesothelioma (ID 710)
- Event: WCLC 2017
- Type: Poster Session with Presenters Present
- Track: Mesothelioma
- Presentations: 1
- Moderators:
- Coordinates: 10/17/2017, 09:30 - 16:00, Exhibit Hall (Hall B + C)
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P2.09-005a - Clinical Characteristics of Early Stage, Malignant Pleural Mesothelioma (ID 10043)
09:30 - 09:30 | Author(s): Yoshiki Negi
- Abstract
Background:
While the mortality rate has markedly improved for primary lung cancer, a disease that used to be incredibly difficult to treat, the prognosis for malignant pleural mesothelioma (MPM) is as poor as ever, with a mean survival time (MST) after diagnosis of about 1 year. Therefore, it is thought that the most practical method of obtaining better survival times than those associated with currently available treatment options is diagnosing MPM at an earlier stage than is possible now. We performed a retrospective study to evaluate the clinical characteristics of early stage MPM.
Method:
The study included 83 patients with a definitive MPM diagnosis of International Mesothelioma Interest Group (IMIG) clinical stage T0-1a/1bN0M0. We selected 40 patients who did not exhibit significant fluorodeoxyglucose (FDG) accumulation (<2.5) in FDG-positron-emission tomography (PET) prior to starting treatment, and then retrospectively examined their clinical characteristics.
Result:
There were 4 women in this study, 5 patients with no history of asbestos exposure, 37 patients with epithelial histology, 3 patients with biphasic histology, and 3 patients with negative cytology. All patients had pleural effusion.
Conclusion:
Although this was a retrospective study, we found that among T0-1a/1bN0M0 and PET-negative MPM patients, positive cytology (class IV/V) and histology (biphasic) were factors associated with a poor prognosis.
