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Henda Neji
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P3.13 - Radiology/Staging/Screening (ID 729)
- Event: WCLC 2017
- Type: Poster Session with Presenters Present
- Track: Radiology/Staging/Screening
- Presentations: 3
- Moderators:
- Coordinates: 10/18/2017, 09:30 - 16:00, Exhibit Hall (Hall B + C)
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P3.13-025 - Spinal Cord and Cauda Equina Compression in Lung Cancer (ID 9946)
09:30 - 09:30 | Presenting Author(s): Henda Neji
- Abstract
Background:
Spinal cord compression is one of the most disabling complications in lung cancer. It may be caused either by the tumor itself or by metastatic involvement of the spine and meninges. The goal of this work is to appreciate characteristic of spinal cord compression in lung cancer.
Method:
Retrospective review of the MRI data of patients with lung cancer presenting with neurological symptoms caused by medullary or cauda equine compression. Only patients with abnormal findings were retained. All exams were performed by a 1.5 T machine.
Result:
From January 2014 to December 2016, only 24 patients (23 males and 1 female) were referred to the imaging department of our institution for medullary compression exploration. Their average age was 57 years. Seventeen patients had adenocarcinoma. Three patients were classed stage IIIB and 18 were classed stage IV. Medullary compression was caused by direct compression (12 cases) of the tumor or by a spine metastases (12 cases). One spine region was involved in 18 patients with dorsal location in 13 patients. In three cases, the compression concerned the cauda equina. Myelopathy was noted in 15 of the 21 patients with spinal cord compression.
Conclusion:
Spinal compression is not frequent in lung cancer. It is mainly observed in advanced stages. It may occur by direct tumor invasion or by vertebral metastatic extension.
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P3.13-026 - Non-Small Cell Lung Cancer: Imaging of Recurrences After Surgery (ID 9983)
09:30 - 09:30 | Presenting Author(s): Henda Neji
- Abstract
Background:
Lung cancer has a poor prognosis unless patients are operated. However, few patients may undergo surgery. Recurrences are not rare and they increase the mortality. The objective of this study is to appreciate the frequency of recurrences after surgery in non-small lung cancer (NSCLC) in our institution and to correlate them to TNM classification and histological subtypes.
Method:
Retrospective review of 127 patients (106 men and 21 women) aged between 19 and 80 years with NSCLC that were operated. All patients had chest, abdomen and brain computed tomography (CT) in their follow up. We precised for each patient the histological type of the lung cancer, the c and p TNM stages, the resection type and the other treatments prescribed, the recurrence site and the delay between the surgery and the recurrence.
Result:
Recurrences were observed in 35 patients (27.5%). They had either a lobectomy (n=30), a pneumonectomy (n=4) or a wedge (n=1). Recurrences were located to the chest in 36 cases (half of them occurred in the operated lung) and in extra-thoracic organs in 13 cases; the brain was the mostly involved. The delay between surgery and recurrence ranged between 1 month and 7 years. Fourteen patients had a recurrence within the first year after surgical removal of their tumor. Recurrences were mostly observed in patients with T4 stage (23%), N3 stage (66.6%), stage III cancer (49%), and with adenocarcinoma. An under-estimation of the cT and cN stages was observed in 5.6% and 27.5% of patients, respectively.
Conclusion:
Recurrences in patients with surgically removed lung cancer are not rare. They depend on its histological type and on the cT and cN stages.
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P3.13-038a - Metastases in T1-T2 classed Lung Cancer (ID 7339)
09:30 - 09:30 | Presenting Author(s): Henda Neji
- Abstract
Background:
Lung cancer is the first cancer responsible for metastases. They can be either intra-or extra-thoracic. Their diagnosis when the cancer is locally non-advanced modifies completely the treatment. The aim of this work is to find out variables influencing metastases occurrence in T1-T2 classed lung cancer.
Method:
Retrospective review of data of 63 patients (60 males and 3 females) with confirmed lung cancer, which were classed T1 or T2 according to the TNM 7 in the work up of their disease and who were explored in the imaging department of our institution between January 2011 and December 2016. Patients were subdivided into two groups: with or without metastases. The variables tested to find out a relationship with metastases occurrence were age, T1 or T2 status, N status and histological type of the cancer. A significant statistical relationship was retained when p was ≤0.05.
Result:
The mean age of the included patients was 61 years (ranging between 43 and 73 years). Adenocarcinoma was the most common histological type (71%). Twenty seven patients (43%) had metastases; 21 of them (77%) had extra-thoracic ones. Comparing patients with and without metastases, no significant relationship was found between the T1 or T2 stage (p= 0.147), the age (p=0.745) and metastases occurrence. In the opposite, they were statistically related to N2-N3 lymph nodes stage (p=0.032) and to adenocarcinoma (p=0.006).
Conclusion:
Metastases are quite frequent in T1-T2 classed lung cancer. Their occurrence was related to the N stage and to the adenocarcinoma.
