Author of

• 20161

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  P1.12 - Pulmonology/Endoscopy (ID 698)

  • Event: WCLC 2017
  • Type: Poster Session with Presenters Present
  • Track: Pulmonology/Endoscopy
  • Presentations: 1
  • Moderators:
  • Coordinates: 10/16/2017, 09:30 - 16:00, Exhibit Hall (Hall B + C)

  • 22752

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    P1.12-005 - Improvement of Performance Status After Therapeutic Bronchoscopy in Patients with Airway Malignancy: Single Center Experience (ID 9699)

    09:30 - 09:30  |  Presenting Author(s): Thitiwat Sriprasart
    • Abstract

    Background:
    Patients with airway involvement by malignancy usually have limited treatment options due to poor performance status. They are at increase risk of mortality when compared with patients without airway involvement. The treatment provided by therapeutic bronchoscopy relieves the airway tumor and leads to improve performance status[1,2]. We report our single center experience of the performance status improvement after therapeutic bronchoscopy in patients with airway malignancy.
    
    Method:
    This is a retrospective review of patients with airway involvement of malignancy either airway obstruction or fistula who underwent therapeutic bronchoscopy from 1 July 2016 to 31 December 2016 at King Chulalongkorn Memorial Hospital. Clinical data including age, sex, type of tumor, bronchoscopic treatment, were recorded. The ECOG performance status before procedure and at 7 days after therapeutic bronchoscopy were reviewed. Complications also reported.
    
    Result:
    43 patients(35 males, 8 females) underwent therapeutic bronchoscopy due to airway involvement of malignancy. The total procedure was 55 procedures. The mean +/- SD age was 62+/- 12 years. Table 1 showed tumor characteristics and therapeutic procedures. Table1: Tumor characteristics and procedures

    Characteristics	Number
    Histology and Origin	43
    Adenocarcinoma Lung	12
    Squamous cell Carcinoma Esophagus	15
    Squamous cell Carcinoma Lung	2
    Small cell Carcinoma	3
    Adenocystic Carcinoma	2
    Anaplastic	1
    Carcinoid	2
    Lymphoma	1
    Metastastic carcinoma (Breast, Sarcoma, Adenocarcinoma)	5
    Airway esophageal fistula	5
    Location
    Trachea	10
    Left main bronchus	11
    Right main bronchus	12
    Carina or diffuse (2or more location)	10
    Procedures	55
    Rigid bronchoscopy with flexible bronchoscopy	16
    Flexible bronchoscopy alone	39
    Nd-Yag laser	33
    Combined Laser with other modalities	22
    Stent placement	15
    Metallic stent	12
    Y stent	3

    The mean +/- SD of ECOG performance status prior to procedure was 3.65+/-1.23. At day 7 after procedure, the mean +/- SD of ECOG performance status was 1.78 +/- 2.24. The ECOG performance status in patients with stent placement prior and after procedure was 4.21 +/-2.01 and 2.85 +/- 1.77 respectively. The patients who received stent placement has poorer ECOG performance status but they received about the same amount of ECOG score improvement when compared with no stent placement. The major complications were bleeding that require intervention (n=3) and respiratory failure(n=1). There was no death in this study.
    
    Conclusion:
    Therapeutic bronchoscopy improved ECOG performance status. The results of treatment can be seen within 7 days after procedure with acceptable complications. References: 1. Chest. 2006 Dec;130(6):1803-7 2. Chest. 2015 May;147(5): 1282-1298