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Taiki Hakozaki
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P1.17 - Thymic Malignancies/Esophageal Cancer/Other Thoracic Malignancies (ID 703)
- Event: WCLC 2017
- Type: Poster Session with Presenters Present
- Track: Thymic Malignancies/Esophageal Cancer/Other Thoracic Malignancies
- Presentations: 1
- Moderators:
- Coordinates: 10/16/2017, 09:30 - 16:00, Exhibit Hall (Hall B + C)
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P1.17-006 - Radiographic Assessment for Tumor Responses of Thymic Carcinoma Using the ITMIG Modified Criteria (ID 8759)
09:30 - 09:30 | Presenting Author(s): Taiki Hakozaki
- Abstract
Background:
Pleural metastases of thymic carcinoma are relatively common, and their unique growth pattern makes accurate and consistent tumor measurement difficult. To minimize intra-observer variability, The ITMIG proposed modified criteria for measurement of tumor response to nonsurgical therapies for thymic carcinoma.
Method:
We conducted a retrospective review of the medical record of advanced or recurrent thymic carcinoma patients treated with chemotherapy between 1980 and 2016 in our institution. The best objective responses were assessed and concorded using the Response Evaluation Criteria in Solid Tumor version 1.1 (RECIST 1.1) and the ITMIG modified criteria.
Result:
27 patients ----. All of 6 patients showing PR assessed by the RECIST criteria remained PR using the ITMIG criteria. Of 19 patients showing SD assessed by RECIST, 18 remained SD and 1 reclassified as PR using the ITMIG criteria. Both of 2 patients showing PD assessed by the RECIST criteria remained PD using the ITMIG criteria. The overall response rate assessed by the two methods did not differ significantly, with kappa value of 0.996.
Conclusion:
ITMIG modified criteria showed a high concordance rate with RECIST 1.1 criteria in response assessment of thymic carcinoma.
