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Sira Laohathai
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P1.16 - Surgery (ID 702)
- Event: WCLC 2017
- Type: Poster Session with Presenters Present
- Track: Surgery
- Presentations: 1
- Moderators:
- Coordinates: 10/16/2017, 09:30 - 16:00, Exhibit Hall (Hall B + C)
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P1.16-005 - Comparison Sublobar vs Lobar Resection in Early Stage Lung Cancer in Octagenarian Patients (ID 8321)
09:30 - 09:30 | Presenting Author(s): Sira Laohathai
- Abstract
Background:
Non-small-cell lung cancer (NSCLC) is a very common disease in the elderly population.Incidence in this particular population is expected to increase further, because of the ageing of the Global population. Numerous studies have shown a benefit of the surgery over medication in octogenrian people.However, limited data are available for the treatment between sublobar vs lobar resection in octagenerian groups. Our object is to compare the overall survival between sublobar vs lobar resection in early stage lung cancer in octogenarian group. Secondary outcome is to demonstrate a disease free survival between sublobar vs lobar resection and Co-morbidity after operation between sublobar vs lobar resection.
Method:
From 2003-2016, a total of 77 patients who age over 80 with stage I non small cell lung cancer and underwent sublobar or lobar resection in Bundang hospital, Seoul university. The clinical data were retrospectively analyzed as regards characteric such as underlying disease, histology, smoking status, pulmonary functiontest, complication and overall survival. Survival was analyzed by the Kaplan-Meier method and log-rank test. Univariate and multivariate logistic regression analyses were performed to identify patient characteristics associated death and recurrence of disease
Result:
Overall survival and overall free disease free survival were similar in both groups.Median follow up time was 24 months However, an incidence of complications after lobar resection was more than sublobar resection with 26.4% and 12.5%, respectively. Patient who recieve sublobar resection had a shorter hospital stay than lobar resection. In multivariate analysis, COPD and family history were a risk factor that associated with recurrence of disease and tumour size, vascular invasion associated with overall mortality.
Conclusion:
Sublobar resection is an alternative treatment for early lung cancer in octogenarians which does not increase risk of recurrence or death after the operation and also could be benefit in shorter period of hospital stay and complication after surgery.
