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Shunsaku Hayai
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P3.12 - Pulmonology/Endoscopy (ID 728)
- Event: WCLC 2017
- Type: Poster Session with Presenters Present
- Track: Pulmonology/Endoscopy
- Presentations: 1
- Moderators:
- Coordinates: 10/18/2017, 09:30 - 16:00, Exhibit Hall (Hall B + C)
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P3.12-001 - Lung Cancer in Patients with Interstitial Lung Disease: Clinical Characteristics and Impact on Survival (ID 7477)
09:30 - 09:30 | Presenting Author(s): Shunsaku Hayai
- Abstract
Background:
Lung cancer (LC) is frequently associated with interstitial lung disease (ILD). However, there are few reports about the frequency or prognostic impact of LC in the ILD patients.
Method:
Patients diagnosed with ILD at Tosei general hospital, from January 2008 to August 2015 were retrospectively reviewed, and a total of 1070 patients with ILD had complete clinical and follow-up data.
Result:
Of the 1070 subjects, 65.8% were male, and the mean age was 68 years. Prevalence of histologically proven lung cancer was 5.6% (n=60). Of the 295 patients with idiopathic pulmonary fibrosis (IPF), 491 with Unclassifiable IIPs (UC-IP), 193 with collagen vascular disease IP (CVD-IP), 6.1% (n=18), 6.1% (n=36) and 2.6% (n=5) were affected by lung cancer. The most frequently encountered histologic types of carcinomas were Adenocarcinomas (n=23, 38%), and squamous cell carcinomas (n=21, 35%). Small-cell lung cancer was encountered for eleven cases (18%). Survival in patients with ILD-LC was significantly worse than in patients with ILD without LC (median survival, 39 months vs 96 months; P<0.001). In patients with UC-IP and with CVD-IP, survival in patients with LC was significantly worse than in patients without LC. However, there was not a significant difference in survivals in patients with IPF (median survival, 42 months vs 54.6 months; P=0.35).
Conclusion:
Prevalence of histologically proven LC was 5.6%. The most frequently encountered histologic types of carcinomas were Adenocarcinomas and squamous cell carcinomas . Survival in patients with LC was worse than without LC. However, in IPF patients, there was not significant difference.
