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Toru Nakamura



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    P3.16 - Surgery (ID 732)

    • Event: WCLC 2017
    • Type: Poster Session with Presenters Present
    • Track: Surgery
    • Presentations: 1
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      P3.16-001 - Feasibility of 20 mL of Saline for Pleural Lavage Cytology in Non-Small Cell Lung Cancer (ID 7400)

      09:30 - 09:30  |  Presenting Author(s): Toru Nakamura

      • Abstract
      • Slides

      Background:
      Pleural lavage cytology (PLC) is an independent prognostic factor for resected non-small cell lung cancer (NSCLC). However, there has been no standard method for the test and the optimal dose of saline is still unclear. We investigated the feasibility of 20 mL saline in this retrospective study.

      Method:
      From January 2001 to December 2011, 466 consecutive patients who underwent a curative resection for NSCLC and received both a pre- and post- PLC by using 20ml of saline were enrolled. The prognostic significance of each PLC status and other clinicopathological factors were investigated.

      Result:
      Patients with a positive pre-(n=24) or post-PLC(n=28) had significantly worse 5-year survival rates than those with negative results (pre-PLC positive/negative; 32.6%/69.9%, p=0.001, post-PLC positive/negative; 21.4%/71.1%, p<0.001, respectively). The post-PLC (p<0.001) was found to be an independent prognostic factor for the overall survival by a multivariate analysis, whereas the pre-PLC was not (p=0.95). In stage I disease, patients with a positive post-PLC had a significantly worse survival regardless of the pre-PLC status. These results were comparable to those of the past reports by using more saline of 50-1000mL.

      Conclusion:
      Using 20 mL of saline would be feasible for PLC and may be helpful to simplify the procedure.

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