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I. Sladić



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    P3.03 - Poster Session with Presenters Present (ID 473)

    • Event: WCLC 2016
    • Type: Poster Presenters Present
    • Track: Mesothelioma/Thymic Malignancies/Esophageal Cancer/Other Thoracic Malignancies
    • Presentations: 1
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      P3.03-058 - A Retrospective Evaluation of 64 Hospitalised Malignant Pleural Mesothelioma (MPM) Patients (ID 5292)

      14:30 - 14:30  |  Author(s): I. Sladić

      • Abstract

      Background:
      Malignant pleural mesothelioma (MPM) is a rare tumour but with increasing incidence and a poor prognosis.Asbestos is the principal aetiological agent of MPM. The aim: To evaluate cases of MPM diagnosed and treated in Clinic for Lung Disease and TB „Podhrastovi“ Clinical Center University of Sarajevo,during 17-year period (1998-2015).

      Methods:
      This retrospective study was performed using a database with 64 patients who had been diagnosed at our Clinic during 1998-2015.The patients were analysed with regard to age,sex,histopathologic type of the tumour,cantonal distribution in Federation of Bosnia and Herzegovina and regimen of treatment.

      Results:
      MPM presented (1-0.2%) 2003-(9-2.0%) 2008 and(9-1.5%) 2011of all hospitalised malignant patients and the greatest number of registered cases was in the year 2008 and 2011.The series included (47-73.4%)male and (17-26.6%)female between 1998-2015.It is evident that cases > 64 years are more frequent (38-59.3%) and 55-64 y.(14-21.8%) and 45-54 y.(10-15.6%).Histopathology types of hospitalised MPM:Epitheloides forms (13-20.3%); Sarcomatoides forms (2-3.13%);Non differentiated pathohistological forms (49-76.5%).Cantonal distribution:Canton Sarajevo is the most frequent (24-37.5%);after which is the ZE-DO canton (18-28.1%);followed by the UNA-SANA canton (10-15.6%). The therapy applied: Chemotherapy was predominant (35-54.6%) particulares Cisplatin+Gemcitabin (21-32.8%); Cisplatin+Alimta (5-7.8%);Chemotherapy + Radiotherapy (10-15.6%); Radiotherapy (4-6.2%); Simptomatic therapy (17-26.5%).

      Conclusion:
      MPM presents 0.2%-2.0% of all hospitalised malignant patients.Male and female at the age of more 64 y.were the most frequent,particularly men.The most number of patients came from Sarajevo.Non-differentiated patohistological forms were the most frequent.Chemotherapy was predominant form of treatment.