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K. Kaur
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P3.01 - Poster Session with Presenters Present (ID 469)
- Event: WCLC 2016
- Type: Poster Presenters Present
- Track: Biology/Pathology
- Presentations: 1
- Moderators:
- Coordinates: 12/07/2016, 14:30 - 15:45, Hall B (Poster Area)
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P3.01-025 - Primary Pulmonary Sarcomas: An Entity Lost in Misdiagnosis (ID 5930)
14:30 - 14:30 | Author(s): K. Kaur
- Abstract
Background:
Primary pulmonary sarcomas are very rare with an incidence rate of <0.5% of all lung malignancies. Their low incidence has impeded comprehensive evaluation of their association with smoking, definitive diagnostic and treatment-regimes. They are often misdiagnosed, both on radiology as well as on fine-needle-aspirate/small-biopsies. We present a series of primary pulmonary sarcomas diagnosed over the last two and a half years.
Methods:
All cases of primary pulmonary sarcomas (2014-2016) were retrieved and reviewed.
Results:
A total of 21 sarcomas were identified. The most common was synovial sarcoma. Four exceptionally rare cases included pulmonary-artery intimal sarcoma, primary pulmonary myxoid sarcoma, malignant peripheral nerve-sheath tumor and follicular dendritic-cell sarcoma. The clinical and pathology details of which are provided in table1. The patients were distributed over a wide-age range (range:9-65 years, median:34 years) with a male-preponderance (M:F=2.2:1). Radiological features were non-specific except in case1(table1). Histopathology revealed spindle-cell tumor in all cases(figure1) and an extensive immunohistochemical-panel and cytogenetic testing was required to clinch the diagnosis. Figure 1 Figure 2
Conclusion:
This is a series of primary thoracic sarcomas with a highlight on four extremely rare cases which bring to light their unique clinical, radiological, histopathological and immunohistochemical findings. Awareness of such entities is essential for proper diagnosis, appropriate molecular-testing and treatment.
