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S. Jamnik
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OA17 - Aspects of Health Policies and Public Health (ID 397)
- Event: WCLC 2016
- Type: Oral Session
- Track: Regional Aspects/Health Policy/Public Health
- Presentations: 1
- Moderators:M. Kneussl
- Coordinates: 12/06/2016, 16:00 - 17:30, Schubert 1
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OA17.05 - Survival in a Cohort of Patients with Lung Cancer: The Role of Age and Gender on Prognosis (ID 6310)
16:45 - 16:55 | Author(s): S. Jamnik
- Abstract
- Presentation
Background:
Lung cancer has a high incidence in Brazil; approximately thirty-four thousand new cases are diagnosed each year. In Brazil, as in other countries, the majority of patients diagnosed with lung cancer are elderly. There are few studies that evaluate demographic and clinical characteristics, disease staging, treatment modalities and survival in young patients, mostly carried out in developed countries. This study aimed to describe these aspects in patients with non-small cell lung cancer (NSCLC) according to age.
Methods:
Retrospective cohort consisted of patients diagnosed with NSCLC followed in a referral hospital in São Paulo. During the monitoring the survival time was evaluated. Survival functions were calculated using the method of Kaplan-Meier. The survival stratified by age was also obtained, according to distribution of percentages (less than 55; between 55 and 72 years; older than 72 years). Differences between survival curves were determined using the log-rank test.
Results:
From January 2000 to July 2015 790 patients were followed, 165 aged less than 55 years, 423 between 55 and 72 years and 202 older than 72 years. Higher incidence of adenocarcinoma was seen at the groups up to 72 years. 575 (73%) patients with advanced disease (IIIB-IV stages) were observed. The median five-year survival was 12 months [46-4]. The survival of patients in different age groups was not different.
*Chi-square test; † Kruskal-Wallis (Duncan test); ‡oneway ANOVA (Bonferroni test).<55 165 >55<72 423 >72 202 p Male n(%) 87 (53) 279 (66) 127 (63) 0.012* Smoke n(%) 136 (82) 363 (86) 165 (82) 0.34* Male 78 (90) 263 (94) 121 (95) 0.21* Female 58 (74) 100 (69) 44 (59) 0.10* Histological type n(%) 0.13* Adenocarcinoma 92 (56) 216 (51) 91 (45) Squamous Cell Carcinoma 52 (32) 170 (40) 91 (45) Staging n(%) 0.057* IA/IIIA 34 (21) 127 (30) 52 (26) IIIB/IV 131 (79) 294 (70) 150 (74) Deaths n (%) 83 (50) 232 (55) 105 (52) 0.56* Follow-up (months) Median[IIQ] 4.9 [1.3-13.2] 6.5 [2.0-16.3] 4.4 [1.4-12.9] 0.07†
Conclusion:
In the age group of younger patients (<55) women predominated, histological type adenocarcinoma was more frequent, and there were more patients with advanced stage at the diagnosis and a higher percentage of smokers in both genders.
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