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M. Zereu



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    P2.05 - Poster Session with Presenters Present (ID 463)

    • Event: WCLC 2016
    • Type: Poster Presenters Present
    • Track: Radiotherapy
    • Presentations: 1
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      P2.05-012 - Definitive Radiotherapy and Survival in Lung Cancer: Results from a Brazillian Cohort Study (ID 4964)

      14:30 - 14:30  |  Author(s): M. Zereu

      • Abstract
      • Slides

      Background:
      Lung Cancer is a major cause of cancer mortality around the world. Many patients are not fit for surgery or chemoradiation, and are treated with radiation therapy alone. There are few data on the outcomes of definitive radiotherapy in Brazil

      Methods:
      All patients AJCC I-III Stage undergoing definitive radiotherapy at the HCPA between 2010 and 2015 were assessed Only individuals unfit for chemotherapy were evaluated. We excluded patients that received surgery. All patients were treated with conformal radiotherapy (3DCRT) and curative intent Individual variables and outcomes were retrospectively evaluated through medical records Statistical analysis was performed with software SPSS 22.

      Results:
      Figure 1

      Patient characteristics N = 68 (%)
      Age, (Mean) 60,22 years
      Gender, No. (%) Men Women 43 (63,2%) 25 (36,7%)
      Race, No (%) White 54 (79,4%)
      AJCC stage, No (%) I II III 5 (7,3%) 26 (38,2%) 37 (54,4%)
      PS ECOG, No (%) 0-2 3-4 44(64,7%) 24 (35,3%)
      Between 2010 and 2015, 68 patients were treated with radiation therapy alone. Most of patients were male and white. The median age at diagnosis was 60,22 years. AJCC Stage III disease was the most prevalent one. The median survival for all stages was 8.055 months (95% CI 5.796 to 10.313 months). Overall survival at 5 years was 11.7 %



      Conclusion:
      Radiotherapy alone resulted in very poor survival in this cohort. Our data is original in Brazil. Most of lung cancer patients who may not tolerate surgery or a chemoradiation regim die. New alternatives for the management of these patients are neceessary.

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