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D. Xhemalaj
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P2.04 - Poster Session with Presenters Present (ID 466)
- Event: WCLC 2016
- Type: Poster Presenters Present
- Track: Mesothelioma/Thymic Malignancies/Esophageal Cancer/Other Thoracic Malignancies
- Presentations: 1
- Moderators:
- Coordinates: 12/06/2016, 14:30 - 15:45, Hall B (Poster Area)
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P2.04-044 - Mediastinal Neurogenic Tumors: Histopathological Characteristics and Surgical Treatment in a Single-Institutional Experience (ID 4169)
14:30 - 14:30 | Author(s): D. Xhemalaj
- Abstract
Background:
Intrathoracic neurogenic tumors are uncommon and typically originate from the peripheral nerves, paraganglionic nerves, or the autonomic nervous system. They are commonly found in the mediastinum, especially in the posterior mediastinum and have a variety of clinical and histological features. Mediastinal neurogenic tumors in adults are generally benign lesions.
Methods:
We retrospectively reviewed our institutional experience of mediastinal neurogenic tumors from 2010 to 2015. The patients were evaluated according to age, gender and histological characteristics of the tumor.
Results:
There were 78% males and 22% females diagnosed with mediastinal neurogenic tumors. Mean age was 48.4±12 years. Distribution according to the histopathological diagnosis was: 56% schwannoma, 22% malignant schwannoma, 22% ganglioneuroma. The operative procedure performed in all cases was tumor extirpation through thoracotomy. In 10% of cases, presence of intraspinal growth was encountered (the so-called "dumbbell tumors"), thus hemilaminectomy was performed. There were no operative deaths and minimal morbidity. Mean postoperative stay was 5 days.
Conclusion:
In this study, the most common mediastinal neurogenic tumor found was schwannoma. Neurogenic tumors arising in the mediastinum are generally of benign nature and mostly found in males. The treatment of choice for malignant and benign mediastinal neurogenic tumors is complete resection for the purposes of avoiding local invasion, facilitating differential histopathological diagnosis and preventing malignant degeneration. The surgical management of the dumbbell tumors differs from others.
