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T. Menju



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    P2.04 - Poster Session with Presenters Present (ID 466)

    • Event: WCLC 2016
    • Type: Poster Presenters Present
    • Track: Mesothelioma/Thymic Malignancies/Esophageal Cancer/Other Thoracic Malignancies
    • Presentations: 1
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      P2.04-012 - A Risk of Death from a Second Cancer Following Complete Resection of Thymoma (ID 4217)

      14:30 - 14:30  |  Author(s): T. Menju

      • Abstract

      Background:
      A portion of patients undergoing complete resection of thymoma develop recurrence of thymoma, while those undergoing thymectomy for thymoma are at risk of developing a second cancer, but it remains unknown whether those patients are more at risk of death from thymoma or from a second cancer.

      Methods:
      Retrospective chart review was performed on our prospectively maintained database of patients undergoing complete resection of thymoma at our institution between 1991 and 2016. Thymoma-specific survival was calculated from thymectomy to death of recurreence of thymoma. Second cancer-specific survival was calculated from thymectomy to death of a second cancer. Both were estimated with Kaplan-Meier method.

      Results:
      Follow-up ranged from 1 to 239 months (median: 54). One hundred and sixty-four patients were identified. During the follow-up, there were four thymoma deaths and 4 deaths from a second cancer. Five-year and 10-year thymoma specific survival was 97.8% and 96.1%, respectively. Five-year and 10-year second cancer specific survival was 98.2% and 96.1%, respectively.

      Conclusion:
      It appears that patients undergoing thymectomy for thymoma are at a similar risk of a second cancer death to that of thymoma death. However, there are too few events during the follow-up and a multi-institutional database is required to more rigorously evaluate both risks.