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Y. Goan



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    P2.04 - Poster Session with Presenters Present (ID 466)

    • Event: WCLC 2016
    • Type: Poster Presenters Present
    • Track: Mesothelioma/Thymic Malignancies/Esophageal Cancer/Other Thoracic Malignancies
    • Presentations: 1
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      P2.04-009 - Tumor Size Did Not Affect Masaoka Staging as Predictors of Recurrence in Thymoma (ID 4849)

      14:30 - 14:30  |  Author(s): Y. Goan

      • Abstract

      Background:
      This single-institution retrospective study assessed the predictive value of Masaoka stage plus tumor size in predicting thymoma recurrence following resection.

      Methods:
      Four models using binary logistic regression were developed for evaluating the relationship of tumor size and Masaoka stage in predicting recurrence. Model I and II included Masaoka stage and median tumor size, respectively. Model III included these two values and their interaction terms (Masaoka stage × medium tumor size). Model IV did not included the interaction between the two parameters as it was not significant.

      Results:
      Model IV was determined to be the best model as it had the lowest -2LogL and used the least number of included parameters. Using Model IV, Masaoka stage positively correlated with recurrence of thymoma (P = 0.001). The risk of recurrence of the patients with Masaoka stage III-IV was significantly higher than that of patients with Masaoka stage I (OR= 36.17, 95% CI: 4.30-304.48, P = 0.001). However, inclusion of tumor size did not influence the predictive value of Masaoka staging for tumor recurrence (P = 0.137).

      Conclusion:
      The data suggest that Masaoka stage plus tumor size is not a better alternative to Masaoka stage alone for tumor recurrence following tumor resection in patients with thymoma.