Author of

• 16935

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  P1.08 - Poster Session with Presenters Present (ID 460)

  • Event: WCLC 2016
  • Type: Poster Presenters Present
  • Track: Surgery
  • Presentations: 1
  • Moderators:
  • Coordinates: 12/05/2016, 14:30 - 15:45, Hall B (Poster Area)

  • 17012

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    P1.08-077 - Comparison of Pulmonary Resection for Lung Cancer after Radical Chemoradiation with That after Induction Chemoradiation (ID 6309)

    14:30 - 14:30  |  Author(s): R. Nakada-Kubota
    • Abstract

    Background:
    Induction chemoradiation (ICR) for advanced non-small cell lung caner is often limited to 45Gy or less to avoid increase of perioperative complications. On the other hand, pulmonary resection after definitive chemoradiotherapy (DCR) is increasing. In this study, we compared three groups, pulmonary resection following low dose ICR (LCR), that following high dose ICR (HCR) and that after DCR.
    
    Methods:
    From 1997 to 2015, we had 24 pulmonary resections following CR. Among 13 ICR, 7 were LCR and 6 were HCR. There were 11 DCR. Intercostal muscle flaps were used in 1 LCR, 6 HCR and 1 DCR. Omental flaps were used in 8 DCR.
    
    Results:
    There was no mortality in any groups. In comparison with LCR and HCR, operation time (min) were 352 and 344, estimated blood loss (ml) were 440 and 280, morbidity (%), 86 and 50. Although operation time was longer (470 min) and there were more blood loss (820 ml) in DCR, there was no significant increase of peri- and post-operative complications. 2-year recurrence free survival and 5-year over all survival rates (%) were 43 and 29 in LCR, 40 and 60 in HCR, and 58 and 52 in DCR.
    
    Conclusion:
    High dose ICR may contribute to better local control and longer survival. Pulmonary resection after DCR is as safe as that following ICR.