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R. Shimizu
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P1.08 - Poster Session with Presenters Present (ID 460)
- Event: WCLC 2016
- Type: Poster Presenters Present
- Track: Surgery
- Presentations: 1
- Moderators:
- Coordinates: 12/05/2016, 14:30 - 15:45, Hall B (Poster Area)
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P1.08-075 - Salvage Surgery for Stage IV Non-Small Cell Lung Cancer (ID 3816)
14:30 - 14:30 | Author(s): R. Shimizu
- Abstract
Background:
There have been few reports regarding salvage surgery in patients with primary lung cancer, and the efficacy of salvage pulmonary resection for primary lung cancer have not been fully elucidated. Furthermore, salvage surgery for stage IV non-small cell lung cancer have been rarely performed. The purpose of this study is to evaluate the efficacy of salvage surgery for stage IV non-small cell lung cancer.
Methods:
We performed a retrospective analysis of 4 patients who underwent salvage pulmonary resection for stage IV non-small cell lung cancer between September, 2002 and September, 2015 at the Shizuoka Cancer Center Hospital.
Results:
Of 2606 cases of surgically resected lung cancer in our hospital, 4 cases (0.15%) of salvage surgery for stage IV non-small cell lung cancer patients were performed. There were 2 men and 2 women. The range of age was 38-63 years old (median 57 years old). The histological type was 3 adenocarcinomas and one large cell carcinoma. The reasons diagnosed stage IV non-small cell lung carcinoma were 2 liver metastasis, 1 brain metastasis, and 1 abdominal lymph node metastasis. All cases have administered chemotherapy, and salvage pulmonary resection was performed for persistent or recurrent primary lung tumors. The median period for surgery from chemotherapy was 17.5 months (range 13-55 months). The lobectomy was performed in all cases. There were no complications after surgery and the mean length of hospital stay was 9 days. Postoperative disease free survival of all patients was 2, 2, 5, 52 months (median 3.5 months), respectively. 3 cases had recurred after surgery and all of them were distant recurrence. 2 cases were died of disease (survival time 15, 42 months, respectively), 1 case was alive with recurrent disease, and 1 case was alive with no recurrent disease (survival time 52 months).
Conclusion:
Although almost all cases had developed distant recurrence after surgery early, one case was long-term survival. Salvage surgery might have been effective for highly selected stage IV non-small cell lung cancer patients.
