Author of

• 16935

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  P1.08 - Poster Session with Presenters Present (ID 460)

  • Event: WCLC 2016
  • Type: Poster Presenters Present
  • Track: Surgery
  • Presentations: 1
  • Moderators:
  • Coordinates: 12/05/2016, 14:30 - 15:45, Hall B (Poster Area)

  • 17003

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    P1.08-068 - Salvage Surgical Resection after Curative-Intent Concurrent Chemoradiothrapy for N2-Stage III Lung Cancer (ID 6035)

    14:30 - 14:30  |  Author(s): Y. Maki
    • Abstract

    Background:
    Background A concurrent chemoradiotherapy (CRT) is thought to be the curative treatment for N2 Stage IIIA locally advanced lung cancer (LALC). However, after the CRT the cancer sometimes remained the treatment field. The radical pulmonary resection of residual cancer after CRT is one of the option for the treatment.
    
    Methods:
    Methods: We retrospectively evaluated 20 patients who received curative-intent CRT and radical surgical resection for LALC from January 2003 to April 2016. The initial treatment for LALC consisted of platinum based 2-drugs with concurrent curative thoracic radiotherapy (60Gy.).
    
    Results:
    Results: The mean age at the surgery was 62.8 years (range 46~ 80 years), two women and 18 men. The mean interval from CRT to the surgery was 25 months (range 3-96 months). All patients except two cases underwent complete surgical resection with mediastinal nodal dissection including lobectomy in 15 cases, lobectomy with bronchoplasty in 2 cases, pneumonectomy in 2 cases and 1 wedge resection. The bronchial stump was covered with pericardial fat tissue or intercostal muscle. Histological type was adenocarcinoma in 11 cases, squamous carcinoma in 6 cases, large-cell-carcinoma in 2 cases, and combined cell type small-cell carcinoma in one case. The mean operation time was 320 minutes (range 163-649 minutes), and mean blood loss was 868g (range 90-6000g). There was no operative mortality and 8 cases post-operative morbidity such as arrhythmia in 4 cases, atelectasis in 2 cases, pneumonia, ileus and heart failure in each. There was no broncho-pleural fistula or bronchial dehiscence. The 3 and 5 years survival after surgical resection was 70% and 60 % with 43 months median follow-up period.
    
    Conclusion:
    Conclusion; The radical pulmonary resection after curative-intent concurrent chemoradiotherapy is feasible with careful patient selection, operative procedure and meticulous perioperative care.