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K. Hata



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    P1.08 - Poster Session with Presenters Present (ID 460)

    • Event: WCLC 2016
    • Type: Poster Presenters Present
    • Track: Surgery
    • Presentations: 1
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      P1.08-067 - The Feasibility of Lung Second Surgery for 2nd Primary Lung Cancer (ID 4113)

      14:30 - 14:30  |  Author(s): K. Hata

      • Abstract

      Background:
      2[nd] primary lung cancer often has been encountered because of improvement of treatment outcome for lung cancer. If close follow up was performed after first surgery, 2[nd] primary lung cancer often was detected in early stage. And local therapy was indicated for this 2[nd] primary lung cancer. However, there is no rule whether stereotactic radiation therapy or surgery should be chosen. The aim of this study was to evaluate the feasibility of second surgery.

      Methods:
      We reviewed retrospectively 123 consecutive patients with past history of lung resection who underwent second surgery for 2[nd] primary lung cancer between 2008 and 2015 at our institution. i) These 123 cases were divided into 2 groups, contralateral and ipsilateral surgery groups. The difference between two groups of surgical difficulties (operation time and blood loss) and feasibility (post-operative complication and length of hospital stay) were evaluated by using Mann-Whitney U-test and Fisher’s exact test. ii) 82 cases who underwent contralateral surgery was picked up and divided into 3 groups, both lobectomy, lobectomy and limited surgery and both limited surgery. The difference between 3 groups of surgical difficulties and feasibility were evaluated by using same methods. iii) Furthermore, 41 cases who underwent ipsilateral surgery divided into 4 groups by procedure: completion pneumonectomy, lobectomy, segmentectomy and wedge resection. The difference between 4 groups of surgical difficulties and feasibility were evaluated by using same methods.

      Results:
      i) Not only operation time (161min vs 123min, p<0.001) but blood loss (30g vs 15g, p=0.002) were more in ipsilateral cases than in contralateral cases significantly. However, there was no significant difference in feasibility. ii) In contralateral cases, there were no significant difference between 3 groups in surgical difficulties and feasibility. iii) In ipsilateral cases, completion pneumonectomy had more operation time and blood loss than other procedures significantly (p=0.005, p=0.002, respectively) However, there was no significant difference in occurrence of post-operative complication.

      Conclusion:
      Ipsilateral surgery, especially completion pneumonectomy for 2[nd] primary lung cancer was more difficult procedure. However, ipsilateral and contralateral surgery was equivalent feasibility. Contralateral 2[nd] primary lung cancer is indication for surgery. However, second surgery for ipsilateral 2[nd] primary lung cancer requires careful consideration.