Author of

• 16935

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  P1.08 - Poster Session with Presenters Present (ID 460)

  • Event: WCLC 2016
  • Type: Poster Presenters Present
  • Track: Surgery
  • Presentations: 1
  • Moderators:
  • Coordinates: 12/05/2016, 14:30 - 15:45, Hall B (Poster Area)

  • 16946

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    P1.08-011 - Feasibility of Surgical Resection for Lung Cancer Patients Aged over 85 Years (ID 5636)

    14:30 - 14:30  |  Author(s): K. Takamochi
    • Abstract

    Background:
    Pulmonary resections for lung cancer in patients aged 80 years or over have been increasing in the aging society, which are accounted for approximately 10% in Japan. Due to the prolonged life expectancy in the elderly, it is inevitable to assess the feasibility of pulmonary resection for lung cancer especially in patients over 85 years in age.
    
    Methods:
    From 1995 to 2015, we underwent 3,099 pulmonary resections for lung cancers in our department. Among them, 213 (6.8%) were aged 80 years or older. They were divided into 2 groups based on the age, i.e., “Over80” who were aged from 80 to 84 and “Over85” who were aged 85 or elder. Clinicopathological factors were analyzed between these two groups, using the t-test or the Chi-squared test. Survivals were calculated by Kaplan-Meier estimation methods.
    
    Results:
    Of the cases, 174 (84%) showed Over80 and 39 (18%) showed Over85. The proportions for male, comorbidity rate, c-stage I disease in the Over85 group were not significantly different than those of the Over80 group (age; 20 (51%) vs. 105 (60%), p=0.189: comorbidity; 36 (92%) vs. 154 (89%), p=0.489: c-stage I; 36 (92%) vs. 143 (82%), p=0.119). The surgical candidates of the octogenarian included 167 (78%) radiological pure-solid lung cancer, however, there was not significant difference between the 2 groups (28 (72%) vs. 139 (80%), p=0.267). Lobectomy was equally performed in 28 (72%) on the Over85 and 126 (72%) of the Over80 (p=0.938), respectively. Perioperative morbidities were observed in 104 (48%) of the patients, though, significant difference was not found between the two study arms (84 (48%) vs. 20 (51%), p=0.734) and the 30-day mortality rates was observed just one patient for the Over80 group. The 5-year overall survival was 51.1% in the Over80 group, 62.6% in the Over85 group (p=0.275), respectively.
    
    Conclusion:
    In the octogenarians, a patient with radiological pure-solid lung cancer was more common as a surgical candidate for the definitive local management. Although proper patient selection and meticulous perioperative management were mandatory for surgical resection of the very elderly, our results support the finding that radical surgical intervention could be feasible even for the patients with high age over 85 years.