Author of

• 16935

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  P1.08 - Poster Session with Presenters Present (ID 460)

  • Event: WCLC 2016
  • Type: Poster Presenters Present
  • Track: Surgery
  • Presentations: 1
  • Moderators:
  • Coordinates: 12/05/2016, 14:30 - 15:45, Hall B (Poster Area)

  • 16941

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    P1.08-006 - Prognostic Impact of Incompletely Lobulated Fissures in Non-Small-Cell Lung Cancer (ID 4231)

    14:30 - 14:30  |  Author(s): J. Usuda
    • Abstract
    • Slides

    Background:
    The division of the incompletely lobulated fissures is often performed during the surgical resection of non-small-cell lung cancer (NSCLC). However, the influence of lobulation on tumor recurrence was unclear in these patients. Therefore, we assessed the prognostic impact of lobulation in patients with NSCLC.
    
    Methods:
    A retrospective study of patients with NSCLC who underwent lobectomy and bi-lobectomy was conducted between April 2008 and May 2016. Patients who underwent division of the interlobar fissure using stapling devices were compared with those who did not undergo division of the interlobar fissure.
    
    Results:
    A total of 126 patients with NSCLC (from p-stage IA to IIIA) who underwent surgery with (n = 103) or without (n = 23) division of the interlobar fissure were included in this analysis. No significant between-group differences were observed with respect to most variables, except for operation side (p = 0.0483), operation time (p = 0.0469), and post-operative lung comorbidity (p = 0.0031).Survival analysis revealed a significant between-group difference in disease-specific survival (DSS; p = 0.0340); however, no significant differences were observed with respect to disease-free survival (p = 0.1372) and overall survival (p = 0.0666).Cox regression univariate analysis revealed a significant association between DSS and the number of staplers used to divide the interlobar fissure (p = 0.0486).
    
    Conclusion:
    In this study, the extent and status of the incompletely lobulated fissures was a significant risk factor for DSS in patients with resected NSCLC.
    
    

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