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R.M. Rosenthal



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    P1.07 - Poster Session with Presenters Present (ID 459)

    • Event: WCLC 2016
    • Type: Poster Presenters Present
    • Track: SCLC/Neuroendocrine Tumors
    • Presentations: 1
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      P1.07-052 - Pulmonary Neuroendocrine Tumors: Single Institution Experience in Brazil (ID 5816)

      14:30 - 14:30  |  Author(s): R.M. Rosenthal

      • Abstract

      Background:
      The primary lung neuroendocrine tumors (NET) are uncommon. They have a wide spectrum of clinical behavior, currently being classified into four types: tumor typical carcinoid (low grade malignancy), atypical carcinoid (intermediate malignancy grade), neuroendocrine large cells carcinoma and small cells. Neuroendocrine lung tumors represent a large and heterogenic group with different management and survival rates. Little information regarding neuroendocrine tumors is available for Latin American countries.

      Methods:
      Retrospective service database review of patients with NET treated at Hospital São Lucas in Porto Alegre, Brazil between 1991-2015. Inclusion criteria were age 18 or older with histologically or immunochemistry confirmed neuroendocrine tumor. For analysis purposes we divided between, typical carcinoid, atypical carcinoid and poorly differentiated (large and small cells).

      Results:
      From January of 1991 to December of 2015, of 946 lung cancer resections 49 patients with NET were resected. Most the patients were female (57,1%), mean age 55 years (28- 84 years). Typical carcinoid represented 63,3% of patients, followed by atypical carcinoid (22,4%) and poorly differentiated neuroendocrine tumors (14,3%). Mean age was 51,4 for typical carcinoid, 56 for atypical carcinoid and 63 for undifferentiated NET. Lobectomy was the surgical approach for 85,7%,, pneumonectomy was required for 4,1% and segmentectomy for 10,2% of patients. Minimally invasive (VATS) was done in 4,1%. Figure 1



      Conclusion:
      According to the European Consensus, pulmonary carcinoids account for 1–2% of all invasive lung malignancies. We found 85,7% of our lung resections were carcinoids and a higher mean age 51,4 for patients with typical and 56 for atypical carcinoids compared to the literature.