Author of

• 16831

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  P1.06 - Poster Session with Presenters Present (ID 458)

  • Event: WCLC 2016
  • Type: Poster Presenters Present
  • Track: Advanced NSCLC
  • Presentations: 1
  • Moderators:
  • Coordinates: 12/05/2016, 14:30 - 15:45, Hall B (Poster Area)

  • 16858

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    P1.06-027 - Retrospective Study of Treatment for Postoperative Local Recurrence of Lung Cancer (ID 4690)

    14:30 - 14:30  |  Author(s): I. Goto
    • Abstract
    • Slides

    Background:
    There is no consensus regarding the standard treatment for postoperative local recurrence of lung cancer. In order to clarify the impact of differences in treatment on patient survival, we conducted a retrospective study of treatment outcomes for patients with postoperative local recurrence of lung cancer.
    
    Methods:
    The subjects of this study were patients who were diagnosed with postoperative local recurrence of lung cancer and treated at our hospital from 2008 to 2014. We divided patients according to treatment regimen, and compared patient characteristics and survival.
    
    Results:
    This study included 38 patients. Among them, 8 received radiation therapy (RT), 10 received chemoradiation therapy (CRT), 18 received chemotherapy (CT), and 2 received best supportive care. The patient characteristics were as follows: median age (range), 71 years (55–84); gender male/female, 30/8; pStage at operation IA/IB/IIA/IIB/IIIA/IIIB, 9/6/9/8/5/1; histology small cell carcinoma/squamous cell carcinoma/adenocarcinoma, 5/12/21. There were no significant differences in patient characteristics between each treatment group. The proportion of patients who experienced disease progression after treatment was 75.0% (6/8) in the RT group, 20.0% (2/10) in the CRT group, and 77.8% (14/18) in the CT group. Progression free survival (PFS) tended to be better in the CRT group than in the other treatment groups. The differences in median PFS (months) were; RT vs CRT: 8.0 vs 15.5, HR=0.210 (95%CI 0.042-1.047), P=0.057; CRT vs CT: 15.5 vs 14.0, HR=0.206 (95%CI 0.047-0.908), P=0.037.
    
    Conclusion:
    In patients with postoperative local recurrence of lung cancer, CRT yielded better outcomes than the other treatments in terms of PFS.
    
    

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