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M. Chen



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    P1.06 - Poster Session with Presenters Present (ID 458)

    • Event: WCLC 2016
    • Type: Poster Presenters Present
    • Track: Advanced NSCLC
    • Presentations: 1
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      P1.06-023 - Clinicopathological Characteristics of Axillary Lymph Node Metastasis in Lung Cancer (ID 3757)

      14:30 - 14:30  |  Author(s): M. Chen

      • Abstract

      Background:
      The morbidity and mortality of lung cancer are rather high. One major metastasis pathway of lung cancer is lymph node metastasis. The incidence of axillary lymph node metastasis(ALNM) is rare, and little is known about its clinicopathological characteristics.

      Methods:
      The clinical data of 91 patients with ALNM who were treated in Zhejiang Cancer Hospital from January 1, 2007 to December 31, 2013 were retrospectively analyzed. The relevance of tumor site、local lymph node site and axillary lymph node site were checked by contingency table. Survival rates were calculated by the Kaplan-Meier method and compared by the log-rank test.

      Results:
      Lung cancer patients with ALNM were often presented with adenocarcinoma(59.3%)、peripheral tumor type(71.4%)、 pleura invasion with pleural effusion(48.4%) or chest wall invasion(52.7%). There was a relationship between tumor site(P<0.001)、local lymph node site(P<0.001) and axillary lymph node site. The median survival time of lung cancer patients with ALNM was 19.02 months, 2-year survival rate is 62.64%. Patients detected with ALNM at the initial diagnose had poorer prognosis (p=0.002). Figure 1Figure 2





      Conclusion:
      ALNM from lung cancer is rare, it may be involved through direct chest wall invasion, spread from supraclavicular and mediastinal lymph node metastasis or systemic origin. Patients detected with ALNM at the initial diagnose had poorer prognosis.