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F. Bogar
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P1.04 - Poster Session with Presenters Present (ID 456)
- Event: WCLC 2016
- Type: Poster Presenters Present
- Track: Pulmonology
- Presentations: 1
- Moderators:
- Coordinates: 12/05/2016, 14:30 - 15:45, Hall B (Poster Area)
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P1.04-011 - Demographic, Clinical and Survival Characteristics of Lung Cancer among Elderly Patients in Turkey (ID 6155)
14:30 - 14:30 | Author(s): F. Bogar
- Abstract
Background:
To determine demographic, clinical and survival data of elderly lung cancer patients.
Methods:
We evaluated 2,637 patients with lung cancer between January 1990 and October 2010. Elderly patients were defined as those 65 years or older. The patients were classified into two groups: younger and older group. The demographic, clinical and survival data of the groups were compared.
Results:
998 (37.8%) patients were in the older group and 1,639 (62.2%) were in the younger group. The female patients rate (9.1% vs 7.8%; p=0.238) and other cancer history (4.4% vs 3.3%; p=0.101), and family cancer history rate (p=0.664) were similar between two groups. Illiterate patients rate (20.1% vs 16.6%; p<0.001), occupational risks (9.2% vs 12.8%; p=0.005), current smoker and exsmoker rate (p<0.001), asbestos exposure rate (p=0.005), COPD prevalence (15.1% vs 8.6%; p<0.001), and two or more comorbidity rate (21.1% vs 10.1%; p<0.001) of older group was higher than younger group. The symptom duration of the groups were 96.4 days and 92.8 days, respectively (p=0.359). Systemic complaints and extrapulmonary intrathoracic spread complaints of older group were higher than younger group (p<0.001 and p=0.025). Karnosfky performance status was lower in older group than younger group (79.3 vs 82.2; p<0.001). Radiological findings of asbestos exposure was higher in the older group than younger group (6.9% vs 4.1%; p=0.002). There was no difference between the groups in terms of histology and stage (p=0.078 and p=0.254). The independent etiological risk factors of lung cancer in elderly patients were lower educational status, smoking, COPD and male gender by multivariable logistic regression analysis. The median survival was 8.0 ± 0.36 months (95% CI: 7,288-8,712) for older group and 9.0 ± 0.27 months (95% CI: 8,477-9,523) for younger group (log-Rank: 4.567; p=0.033). The factors affecting survival in the both groups stage, Karnofsky performance status and treatment by Cox regression analysis.
Conclusion:
These data indicate that lung cancer had different risk factors and short survival in elderly patients. These features should be considered in the management of these patients.
