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B. Miron
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P1.04 - Poster Session with Presenters Present (ID 456)
- Event: WCLC 2016
- Type: Poster Presenters Present
- Track: Pulmonology
- Presentations: 1
- Moderators:
- Coordinates: 12/05/2016, 14:30 - 15:45, Hall B (Poster Area)
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P1.04-010 - Neutrophil to Lymphocyte, Platelet to Lymphocyte Ratios and Systemic Inflammation in Lung Cancer Stages (ID 6169)
14:30 - 14:30 | Author(s): B. Miron
- Abstract
Background:
Lung cancer is associated with systemic inflammation which seems to influence the prognostic of the disease. Different affordable methods may be used to evaluate the systemic inflammation: erythrocyte sedimentation rate (ESR), Neutrophil to lymphocyte ratio (Ne/Ly), Platelet to lymphocyte ratio (Pl/Ly). The aim of the study is to assess the relation between TNM lung cancer stages and the systemic inflammation estimated by Ne/Ly, Pl/Ly and ESR.
Methods:
Patients with lung cancer were classified according to 7[th] TNM lung cancer staging in two groups: Group A (I, II and IIIA) and Group B (IIIB, IV). A complete blood count (CBC) and ESR were determined. Ne/Ly and Pl/Ly ratios were calculated for all patients. The results were compared between the two groups.
Results:
73 consecutive patients (22 in Group A and 51 in group B) were analyzed. In Group A (16 males), the mean age was 63,73 ± 7,69 years, the median Ne/Ly: 2,86 (0,88-8,36), median Pl/Ly: 128,81 (21,62-416,67) and median ESR: 10 mm/h (10-120). In Group B (48 males), the mean age was 65,06 ± 10,09 years, the median Ne/Ly: 4,46 (0,70-25,6), median Pl/Ly: 204,48 (3,38-651,25) and median ESR: 40 mm/h (3-120). The values of Ne/Ly, Pl/Ly were significantly higher (p: 0,009 respectively p: 0,007) in Group B versus Group A, but no statistically significant difference was observed for ESR values.
Conclusion:
We found a relation between TNM lung cancer stages and the systemic inflammation assessed by neutrophil to lymphocyte (Ne/Ly) and platelet to lymphocyte (Pl/Ly) ratios. The values of Ne/Ly, Pl/Ly ratios were significantly higher in nonresectable stages (IIIB, IV).Erythrocyte sedimentation rate (ESR) seems not to be an appropriate method to evaluate this relation.
