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J. Kowalewski



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    P1.03 - Poster Session with Presenters Present (ID 455)

    • Event: WCLC 2016
    • Type: Poster Presenters Present
    • Track: Radiology/Staging/Screening
    • Presentations: 1
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      P1.03-058 - Cost-Effectiveness of CT Screening in the Early Detection of Lung Cancer (ID 5862)

      14:30 - 14:30  |  Author(s): J. Kowalewski

      • Abstract
      • Slides

      Background:
      Screening using computerized tomography of the chest for an early detection of lung cancer has been performed worldwide since decades, but only two years ago, after proving in a prospective randomized study that it prolongs survival of the study population, it received the recommendation of scientific societies. However, the issue of cost-effectiveness of this screening remains open.

      Methods:
      A review of several cost-effectiveness analyses of lung cancer screening with low-dose CT available in the literature was performed. We also conducted our own cost-effectiveness analysis on the basis of epidemiological data and data from the National Health Fund concerning the type, number and cost of medical procedures reimbursed for lung cancer patients.

      Results:
      The results of cost-effectiveness analyses carried out in different countries are equivocal and depend mainly on the inclusion and exclusion criteria, methods of analysis and prices of medical procedures. More recent analyses, performed in different countries, indicate high profitability of this screening. In our study, the cost of early detection of one lung cancer using CT scan is comparable to the cost of a detection of one breast cancer using mammography and is about 3,400 Euro. The incremental cost-effectiveness ratio (ICER) in our analysis is about 1180 Euro / life year gained.

      Conclusion:
      As the widely accepted limit of cost-effectiveness is three times the gross national product per capita / life year gained, lung cancer screening with low-dose CT in Poland should be considered highly cost-effective. In future screening programs, high cost-effectiveness can be achieved by strict adherence to inclusion and exclusion criteria. To ensure this, screening should be performed either as prospective observatory non-randomized clinical trials or in dedicated screening centers. To ensure low level of false positive and false negative results, radiologists in screening centers should be equipped with software for measuring and monitoring the volume of pulmonary nodules.

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