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Y. Sugita



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    P1.03 - Poster Session with Presenters Present (ID 455)

    • Event: WCLC 2016
    • Type: Poster Presenters Present
    • Track: Radiology/Staging/Screening
    • Presentations: 1
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      P1.03-026 - Measurement of Pulmonary Artery on CT to Predict Acute Exacerbation of Interstitial Pneumonia after Pulmonary Resection for Lung Cancer (ID 4882)

      14:30 - 14:30  |  Author(s): Y. Sugita

      • Abstract
      • Slides

      Background:
      Interstitial pneumonia (IP) is often accompanied by pulmonary hypertension (PH) that is considered to be fatal and has relation to acute exacerbation. To diagnose PH, right heart catheterization is generally required, but it is invasive. Nowadays pulmonary artery diameter (dPA) and the ratio of dPA to ascending aorta diameter (rPA) measured by CT are reported to be indicators of PH. We examined whether dPA and rPA could be predictors of acute exacerbation of IP after pulmonary resection for lung cancer.

      Methods:
      We retrospectively analyzes 97 patients with IP who had undergone pulmonary resection for lung cancer at Tokyo Medical and Dental University between July 2010 and December 2015. We examined sex, surgical procedures, KL-6, surfactant protein D, post-operative prolonged airleakage, combined pulmonary fibrosis and emphysema (CPFE), percent diffusing capacity of lung for carbon monoxide (%DLCO), dPA and rPA.

      Results:
      The mean age was 71 years (range, 43-86 years), and 79 patients were males and 18 were females. 47 patients was diagnosed with CPFE before surgery. Acute exacerbation occurred in 8 patients. Univariate analysis revealed that CPFE, %DLCO and rPA were predictors of acute exacerbation after surgery. In multivariate analysis, CPFE and rPA were identified as independent predictors of acute exacerbation after surgery (p=0.046 and 0.036, respectively).

      Conclusion:
      In interstitial pneumonia, rPA measured by CT is effective to predict acute exacerbation after pulmonary resection for lung cancer.

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