Author of

• 16489

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  P1.01 - Poster Session with Presenters Present (ID 453)

  • Event: WCLC 2016
  • Type: Poster Presenters Present
  • Track: Epidemiology/Tobacco Control and Cessation/Prevention
  • Presentations: 1
  • Moderators:
  • Coordinates: 12/05/2016, 14:30 - 15:45, Hall B (Poster Area)

  • 16543

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    P1.01-054 - Lung Cancer: Histology, Gender and Age Changes Over Past 30 Years in Brazil (ID 6286)

    14:30 - 14:30  |  Author(s): J.O. Rios
    • Abstract

    Background:
    Lung is the leading death cause cancer related worldwide when considering both genders. The great effort to reduce smoking and introduce of cigarette changed lung cancer epidemiology. In developed countries the increase of adenocarcinoma and decrease of squamous cell carcinoma are well known. Other characteristic reported is the rising number of with the disease. Better understanding of current lung cancer epidemiology is necessary to design public health strategies for prevention, diagnosis and treatment.
    
    Methods:
    Retrospective analysis of all patients with non small cell lung cancer submitted to anatomical lung resection between 1986 and 2015 in an University Hospital of South Brazil. Patients were divided in three periods 1986-1995, 1996-2005 and 2006-2015. The same pathologist group made histology diagnosis and all staging was updated according to the new IASLC 7th edition. All analyses were performed using the SAS program.
    
    Results:
    In our Institution 1030 patients underwent anatomical lung resection for lung cancer between 1986 and 2015. 64.5% were males, average age 62.1 years, 40.6% squamous cell carcinoma and 44.5% adenocarcinoma, 23% advanced stage IIIA. The female proportion increased from 26.6% on first period to 44.2% on last period. Mean age at surgery treatment was 56.4 years for women and 58.9 for men on first period, and 62.2 for woman and 64.6 for men on the last period (p<0.001). The proportion of squamous cell changed from initially 49.6%, then 43% to 34.8% on the last period (p<0.001). In comparison in the same sequence we have for adenocarcinoma prevalence starting on 38.1%, 41.2% and most recently 49.5%. Stage IIIA was predominant on all periods with 23%, however early stages IA and IB combined represent 47.1% in the last group. Type of surgery was predominantly lobectomy and was verified decreasing in pneumonectomy rate.
    
    Conclusion:
    Analyses including gender showed that lung cancer in women is raising over the years but didn’t surpassed men yet. Women adenocarcinoma has increased the participation on total cases. The significant decrease of pneumonectomy reinforces the changes on surgical management technics and also correlates with more early staging diagnosis. The mean average age on surgery has increased for both men and women.