Author of

• 16489

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  P1.01 - Poster Session with Presenters Present (ID 453)

  • Event: WCLC 2016
  • Type: Poster Presenters Present
  • Track: Epidemiology/Tobacco Control and Cessation/Prevention
  • Presentations: 1
  • Moderators:
  • Coordinates: 12/05/2016, 14:30 - 15:45, Hall B (Poster Area)

  • 16542

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    P1.01-053 - Lung Cancer in Brazil: Men and Women Differences (ID 6270)

    14:30 - 14:30  |  Author(s): G.M. Schwarcke
    • Abstract

    Background:
    The objective of this study was to describe the trends of histology and age of patients with non-small cell lung cancer (NSCLC) treated with lung resection according to gender. The histology of lung cancer is changing in developed countries and there is still little information available for developing countries.
    
    Methods:
    Retrospective analysis of all patients (N=1030) with resected NSCLC between 1986 and 2015 in a university hospital of Southern Brazil. Differences in histology, stage and type of surgery were analyzed by sex and period (1986-1995, 1996-2005 and 2006-2015).
    
    Results:
    Most patients were males (64.5%), main histologic types were adenocarcinoma (44.5%) and squamous cell carcinoma (40.6%). Mean age at surgery was 56.5 years for women and 58.9 years for men in first period, and 62.2 for women and 64.6 for men in the last period (p<0.001), suggesting that it was approximately 2.4 years higher for men (p<0.001), in spite of the period. The proportion of histologic types were different by gender (p<0.001), showing that overall squamous cells carcinoma was more frequent in men (46.9%) than in women (29%), and the opposite occurred for adenocarcinoma (40.4% versus 51.8% for men and women, respectively). Analyses by period showed squamous cells carcinoma declined from around 38.9% in the first period to 23.2% in 2005-2015 for men, virtually equaling the proportion of adenocarcinoma in the last period. The proportion of adenocarcinoma in women increased from 11.9% in the first period to 24% in the last. Considering all NSCLC patients, females with adenocarcinoma represented 11.9% in the first and 24% in the last period. Figure 1
    
    
    
    Conclusion:
    As seen in developed countries, rates of lung cancer in females are rising over the last three decades, but have not surpassed men rates yet. Adenocarcinoma is consistently the most frequent histological type in women. In men squamous cell rate has decreased.