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  P3.08 - Poster Session/ Thymoma, Mesothelioma and Other Thoracic Malignancies (ID 226)

  • Event: WCLC 2015
  • Type: Poster
  • Track: Thymoma, Mesothelioma and Other Thoracic Malignancies
  • Presentations: 1
  • Moderators:
  • Coordinates: 9/09/2015, 09:30 - 17:00, Exhibit Hall (Hall B+C)

  • 15598

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    P3.08-021 - Bronchopulmonary Carcinoid: A Developing Nation Cancer Center's Perspective  (ID 2765)

    09:30 - 09:30  |  Author(s): D. Pandey
    • Abstract
    • Slides

    Background:
    Bronchopulmonary carcinoids are low grade malignant tumours and increased incidence has been noticed worldwide. Our aim was to study preoperative characteristics, surgical approaches and outcome in bronchopulmonary carcinoid patients treated at a institutional cancer center.
    
    Methods:
    Twenty patients with bronchopulmonary carcinoids were surgically treated at department of surgical oncology, IRCH, AIIMS between December 2006 and December 2014. Preoperative variables, postoperative outcome and histopathological features were analyzed retrospectively. All patients underwent a detailed clinical evaluation followed by CECT of chest and bronchoscopy with biopsy of the suspicious lesion. After preoperative optimization, all patients were treated with upfront surgery. Adjuvant chemotherapy was given in patients with lymph nodal metastasis. Patients were followed up at three monthly interval with Clinical examination, chest X ray and serum chromogranin in cases of suspected recurrence. Because of cost factors Dotanoc scans were done only in cases with radiological suspicion of recurrence.
    
    Results:
    Patient’s median age was 40 years (range 18-62 years). All patients were symptomatic and median duration of symptoms before presentation was 18 months (range 6-72 months). Eight patients were treated with antitubercular drugs after presumptive diagnosis outside based on symptoms and Xrays. All the patients had lobar or main bronchial involvement which was detected on bronchoscopy and biopsy. Ninteen patients underwent complete pulmonary resection with mediastinal nodal dissection and surgical approach included eight pneumonectomies, four bilobectomies, five lobectomies, two sleeve resections. After a median follow up of 15 months, all patients were alive with no local recurrence or distant metastasis. On Histopathology all the resections margins were free of tumor and lymph nodal involvement was found in one patient.
    
    Conclusion:
    Delayed presentation and misdiagnosis are major concern in our scenario because of high prevalence of tuberculosis and despite a small number of cases our study emphasises the need for early bronchoscopy in patients with persistent symptoms. Aggressive surgical resection with technical approach of lung preservation may provide optimal survival results
    
    

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