Author of

• 15558

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  P3.07 - Poster Session/ Small Cell Lung Cancer (ID 223)

  • Event: WCLC 2015
  • Type: Poster
  • Track: Small Cell Lung Cancer
  • Presentations: 1
  • Moderators:
  • Coordinates: 9/09/2015, 09:30 - 17:00, Exhibit Hall (Hall B+C)

  • 15565

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    P3.07-007 - Clinical Effect Observation of Compound Kushen Injection Combined with EP Regimen Chemotherapy for Small Cell Lung Cancer (SCLC) (ID 1045)

    09:30 - 09:30  |  Author(s): Z. Yao
    • Abstract

    Background:
    To observe the clinical efficacy of Compound Kushen Injection combined with EP regimen chemotherapy for the treatment of small cell lung cancer SCLC).
    
    Methods:
    98 cases of small cell lung cancer patients were chosen and randomly divided into experimental group and control group. 49 patients in experimental group were treatment with Compound Kushen Injection combined with EP regimen chemotherapy. 49 patients in control group received EP regimen chemotherapy alone. Both groups were repeated every 4 weeks and 3 cycles. All patients completed efficacy evaluation after treatment 3 cycles.
    
    Results:
    There was no significant difference in short-term effect between the two groups( P＞0.05). The gastrointestinal reactions(represented as vomiting, anepithymia and diarrhea) and bone marrow depression(the toxicity on hemoglobin, leukocyte and platelet) in experimental group were alleviated compared with those in control group. There was significant difference between the two groups (P＜0.05). The median survival time was 462d in experimental group while 268d in control group( P＜0.05). KPS score after chemotherapy in all experiment groups was significantly higher than that in control group( P＜0.05).
    
    Conclusion:
    Compound Kushen Injection combine with EP regimen chemotherapy shows precise therapeutic effect on SCLC, reducing adverse drug reactions, increasing median survival time and improving the life quality of patients.