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H.I. Yoon
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P3.02 - Poster Session/ Treatment of Localized Disease – NSCLC (ID 211)
- Event: WCLC 2015
- Type: Poster
- Track: Treatment of Localized Disease - NSCLC
- Presentations: 1
- Moderators:
- Coordinates: 9/09/2015, 09:30 - 17:00, Exhibit Hall (Hall B+C)
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P3.02-018 - Factors Associated with Preserved Pulmonary Function in Non-Small Cell Lung Cancer Patients after Video-Assisted Thoracic Surgery (ID 157)
09:30 - 09:30 | Author(s): H.I. Yoon
- Abstract
Background:
Some non-small cell lung cancer (NSCLC) patients showed preserved pulmonary function after surgery. Video-assisted thoracic surgery (VATS) is currently widely performed and well known to preserve pulmonary function compared to open thoracotomy. However, it is unknown which factors are associated with the preservation of pulmonary function after VATS in NSCLC patients.
Methods:
Three hundred and fifty one patients with NSCLC who underwent VATS were enrolled. Pulmonary function tests were performed preoperatively and at 12 months postoperatively. Patients who showed preserved forced expiratory volume in 1 second (FEV~1~) and diffusing capacity of carbon monoxide (DLCO) were compared with patients who did not.
Results:
FEV~1~ was preserved after VATS in 65 (18.5 %) patients. They were significantly related to undertake VATS sublobar resection (P<0.001) and resect at right upper lobe (RUL) or right middle lobe (RML) (P<0.05) in multivariable analysis. DLCO showed preservation in 95 (27.1%) patients. VATS sublobar resection (P=0.005), lower baseline DLCO (P<0.001) and RUL or RML resection (P<0.05) were significantly associated with DLCO preservation in multivariable analysis.
Conclusion:
For the preservation of pulmonary function after NSCLC surgery, VATS sublobar resection was superior to VATS lobectomy and the surgical location of RUL or RML was superior to other sites.
